Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RPS6KA2 | Q15349 | 15/20 | 0.53 |
| ▸ | MAPKAPK2 | P49137 | 4/20 | 0.52 |
| ▸ | RPS6KA3 | P51812 | 11/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17361155 | 0.84 | MAPKAPK2 (0.54) | RPS6KA2MAPKAPK2RPS6KA3 | |
| SCHEMBL16123161 | 0.84 | MAPKAPK2 (0.54) | RPS6KA2MAPKAPK2RPS6KA3 | |
| SCHEMBL16123122 | 0.84 | MAPKAPK2 (0.54) | RPS6KA2MAPKAPK2RPS6KA3 | |
| SCHEMBL16123159 | 0.84 | MAPKAPK2 (0.54) | RPS6KA2MAPKAPK2RPS6KA3 | |
| SCHEMBL16123265 | 0.84 | MAPKAPK2 (0.55) | RPS6KA2MAPKAPK2RPS6KA3 | |
| SCHEMBL16100908 | 0.84 | MAPKAPK2 (0.55) | RPS6KA2MAPKAPK2RPS6KA3 | |
| SCHEMBL17361141 | 0.84 | MAPKAPK2 (0.55) | RPS6KA2MAPKAPK2RPS6KA3 | |
| SCHEMBL17371360 | 0.82 | MAPKAPK2 (0.57) | RPS6KA2MAPKAPK2RPS6KA3 | |
| SCHEMBL16123263 | 0.82 | MAPKAPK2 (0.54) | RPS6KA2MAPKAPK2RPS6KA3 | |
| SCHEMBL17361118 | 0.82 | MAPKAPK2 (0.54) | RPS6KA2MAPKAPK2RPS6KA3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20150376208-A1 | MK2 INHIBITORS AND USES THEREOF | CELGENE AVILOMICS RESEARCH, INC. (US) | 2015-12-31 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150376208-A1 | MK2 INHIBITORS AND USES THEREOF | MKNK2, DUSP2, MKNK1 | RPS6KA2 11/4885MAPKAPK2 7/4885RPS6KA3 75/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.