Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BUB1 | O43683 | 20/20 | 0.85 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17371779 | 0.92 | BUB1 (1.00) | BUB1 | |
| SCHEMBL17372101 | 0.90 | BUB1 (1.00) | BUB1 | |
| SCHEMBL17379678 | 0.87 | BUB1 (1.00) | BUB1 | |
| SCHEMBL17372386 | 0.84 | BUB1 (1.00) | BUB1 | |
| SCHEMBL17379690 | 0.83 | BUB1 (0.86) | BUB1 | |
| SCHEMBL17371979 | 0.82 | BUB1 (1.00) | BUB1 | |
| SCHEMBL17372479 | 0.82 | BUB1 (1.00) | BUB1 | |
| SCHEMBL17372063 | 0.81 | BUB1 (1.00) | BUB1 | |
| SCHEMBL17371791 | 0.81 | BUB1 (0.67) | BUB1 | |
| SCHEMBL17372276 | 0.79 | BUB1 (1.00) | BUB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3157914-A1 | 3-AMINO-1,5,6,7-TETRAHYDRO-4H-INDOL-4-ONES | Bayer Pharma Aktiengesellschaft (DE) | 2017-04-26 | — | — | EP | claimed |
| WO-2015193339-A1 | 3-AMINO-1,5,6,7-TETRAHYDRO-4H-INDOL-4-ONES | BAYER PHARMA AKTIENGESELLSCHAFT (DE) | 2015-12-23 | — | — | WO | claimed |
| EP-3157914-A1 | 3-AMINO-1,5,6,7-TETRAHYDRO-4H-INDOL-4-ONES | Bayer Pharma Aktiengesellschaft (DE) | 2017-04-26 | — | — | EP | disclosed |
| WO-2015193339-A1 | 3-AMINO-1,5,6,7-TETRAHYDRO-4H-INDOL-4-ONES | BAYER PHARMA AKTIENGESELLSCHAFT (DE) | 2015-12-23 | — | — | WO | disclosed |