SCHEMBL17372978

SCHEMBL17372978

CCCCCCCC/C=C\CCCCCCCC(=O)Oc1c(C(C)C)cccc1C(C)C

nearest known ligand 0.57

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
▸ POLM Q9NP87 1/20 0.57
▸ POLK Q9UBT6 1/20 0.57
▸ POLL Q9UGP5 1/20 0.57
▸ POLH Q9Y253 1/20 0.57
▸ HTR2A P28223 1/20 0.48
▸ FAAH O00519 1/20 0.47
▸ EPHX2 P34913 1/20 0.47
▸ ELANE P08246 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17372982 0.92 POLM (0.51) POLMPOLKPOLLPOLH
SCHEMBL27709035 0.91 POLM (0.49) POLMPOLKPOLLPOLH
SCHEMBL15547990 0.85 POLM (0.54) POLMPOLKPOLLPOLH
SCHEMBL15549156 0.85 POLM (0.54) POLMPOLKPOLLPOLH
SCHEMBL15548101 0.84 POLM (0.52) POLMPOLKPOLLPOLH
SCHEMBL8176584 0.83 POLM (0.57) POLMPOLKPOLLPOLHFAAH
SCHEMBL30666136 0.81 POLM (0.67) POLMPOLKPOLLPOLHHTR2A
SCHEMBL15558627 0.80 KDM4E (0.55) POLMPOLKPOLLPOLH
SCHEMBL6535664 0.79 SCN5A (0.44) —
SCHEMBL14815784 0.79 SCN5A (0.44) —

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115463106-A Solid oral dosage forms of lipophilic compounds 索露奥公司 2022-12-13 — — CN disclosed
US-11197828-B2 Solid oral dosage form of lipophilic compounds Solural Pharma ApS (DK) 2021-12-14 — — US disclosed
EP-3157508-B1 SOLID ORAL DOSAGE FORM OF LIPOPHILIC COMPOUNDS Solural Pharma ApS (DK) 2020-12-09 — — EP disclosed
US-20170119674-A1 SOLID ORAL DOSAGE FORM OF LIPOPHILIC COMPOUNDS Solural Pharma ApS (DK) 2017-05-04 — — US disclosed
EP-3157508-A2 SOLID ORAL DOSAGE FORM OF LIPOPHILIC COMPOUNDS Solural Pharma Aps (DK) 2017-04-26 — — EP disclosed
WO-2015193380-A2 SOLID ORAL DOSAGE FORM OF LIPOPHILIC COMPOUNDS Solural Pharma ApS (DK) 2015-12-23 — — WO disclosed
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