Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSK3B | P49841 | 9/20 | 0.63 |
| ▸ | ACHE | P22303 | 1/20 | 0.50 |
| ▸ | QPCT | Q16769 | 1/20 | 0.49 |
| ▸ | SPHK2 | Q9NRA0 | 1/20 | 0.49 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.48 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
| ▸ | ADCY1 | Q08828 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | ATR | Q13535 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.46 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.46 |
| ▸ | CXCR5 | P32302 | 1/20 | 0.46 |
| ▸ | APLNR | P35414 | 1/20 | 0.46 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.46 |
| ▸ | CCR6 | P51684 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17377350 | 1.00 | GSK3B (0.63) | GSK3BACHEQPCTSPHK2HDAC6 | |
| SCHEMBL19077663 | 0.90 | GSK3B (0.60) | GSK3BACHEQPCTSPHK2HDAC6 | |
| SCHEMBL17377394 | 0.85 | NPC1 (0.53) | KDM4EADCY1SMN1; SMN2LMNAPTGS2 | |
| SCHEMBL17377396 | 0.85 | NPC1 (0.53) | KDM4EADCY1SMN1; SMN2LMNAPTGS2 | |
| SCHEMBL17377364 | 0.85 | GSK3B (0.62) | GSK3BACHEQPCTSPHK2HDAC6 | |
| SCHEMBL17383549 | 0.85 | GSK3B (0.62) | GSK3BACHEQPCTSPHK2HDAC6 | |
| Hydrochloric Acid SCHEMBL17377355 | 0.84 | GSK3B (0.61) | GSK3BACHEQPCTSPHK2HDAC6 | |
| SCHEMBL3532271 | 0.80 | SPHK2 (0.74) | GSK3BACHEQPCTSPHK2HDAC1 | |
| SCHEMBL17377392 | 0.80 | SPHK2 (0.74) | GSK3BACHEQPCTSPHK2HDAC1 | |
| SCHEMBL17377351 | 0.79 | GSK3B (0.61) | GSK3BACHEQPCTSPHK2HDAC6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9828351-B2 | Enzyme interacting agents | MONASH UNIVERSITY (AU) | 2017-11-28 | — | — | US | disclosed |
| US-20170190698-A1 | ENZYME INTERACTING AGENTS | CENTRAL ADELAIDE LOCAL HEALTH NETWORK INCORPORATED (AU) | 2017-07-06 | — | — | US | disclosed |
| EP-3160949-A1 | ENZYME INTERACTING AGENTS | Monash University (AU) | 2017-05-03 | — | — | EP | disclosed |
| WO-2015196258-A1 | ENZYME INTERACTING AGENTS | MONASH UNIVERSITY (AU) | 2015-12-30 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170190698-A1 | ENZYME INTERACTING AGENTS | SMPD1, SMPD2, ASAH1 | GSK3B 3195/4885ACHE 430/4885QPCT 980/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.