Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 7/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | LPAR1 | Q92633 | 2/20 | 0.32 |
| ▸ | LPAR3 | Q9UBY5 | 2/20 | 0.32 |
| ▸ | TP53 | P04637 | 2/20 | 0.32 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL296574 | 0.75 | TSHR (0.67) | TSHRALDH1A1CYP3A4HPGDLPAR3 | |
| SCHEMBL15032666 | 0.74 | TSHR (0.41) | TSHRALDH1A1CYP3A4HPGDLPAR3 | |
| SCHEMBL5050857 | 0.74 | TSHR (0.70) | TSHRALDH1A1CYP3A4HPGDLPAR3 | |
| SCHEMBL2943780 | 0.74 | TSHR (0.70) | TSHRALDH1A1CYP3A4HPGDLPAR3 | |
| SCHEMBL31050900 | 0.74 | TSHR (0.70) | TSHRALDH1A1CYP3A4HPGDLPAR3 | |
| SCHEMBL28268629 | 0.74 | TSHR (0.70) | TSHRALDH1A1CYP3A4HPGDLPAR3 | |
| SCHEMBL15032975 | 0.71 | TSHR (0.47) | TSHRALDH1A1CYP3A4HPGDLPAR1 | |
| SCHEMBL16362481 | 0.71 | TSHR (0.41) | TSHRALDH1A1CYP3A4HPGDTP53 | |
| SCHEMBL42398 | 0.70 | TSHR (0.63) | TSHRALDH1A1CYP3A4HPGDLPAR3 | |
| SCHEMBL15032660 | 0.69 | TSHR (0.44) | TSHRALDH1A1CYP3A4HPGDTP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10221274-B2 | Polyurethanes, articles comprising the same and methods of manufacture thereof | UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INCORPORATED (US) | 2019-03-05 | — | — | US | disclosed |
| US-20170152338-A1 | POLYURETHANES, ARTICLES COMPRISING THE SAME AND METHODS OF MANUFACTURE THEREOF | UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INC. (US) | 2017-06-01 | — | — | US | disclosed |
| WO-2015200591-A1 | POLYURETHANES, ARTICLES COMPRISING THE SAME AND METHODS OF MANUFACTURE THEREOF | UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INC. (US) | 2015-12-30 | — | — | WO | disclosed |