SCHEMBL1737786

SCHEMBL1737786

CCn1c(C)c(C)c2cc(C(=O)N3CCC(CO)CC3)nc(N3CCc4ccccc4C3)c21

nearest known ligand 0.45

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 2/20 0.45
KMT2A Q03164 2/20 0.45
RECQL P46063 1/20 0.40
HTR2C P28335 11/20 0.39
ALDH1A1 P00352 2/20 0.39
HPGD P15428 2/20 0.39
LMNA P02545 2/20 0.39
GAA P10253 1/20 0.39
HTR2A P28223 1/20 0.39
TSHR P16473 1/20 0.38
MAPK1 P28482 1/20 0.38
AKR1C3 P42330 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL1736882 0.99 MEN1 (0.45) MEN1KMT2ARECQLHTR2CALDH1A1
SCHEMBL1737132 0.94 MEN1 (0.44) MEN1KMT2ARECQLALDH1A1HPGD
Hydrochloric Acid SCHEMBL1738424 0.93 MEN1 (0.43) MEN1KMT2ARECQLALDH1A1HPGD
SCHEMBL1736547 0.92 MEN1 (0.47) MEN1KMT2ARECQLALDH1A1HPGD
Hydrochloric Acid SCHEMBL1737987 0.91 MEN1 (0.46) MEN1KMT2ARECQLALDH1A1HPGD
SCHEMBL1737695 0.90 MEN1 (0.49) MEN1KMT2ARECQLALDH1A1HPGD
Hydrochloric Acid SCHEMBL1738353 0.89 MEN1 (0.48) MEN1KMT2ARECQLALDH1A1HPGD
SCHEMBL1739692 0.89 MEN1 (0.48) MEN1KMT2ARECQLALDH1A1HPGD
SCHEMBL1738730 0.89 MEN1 (0.48) MEN1KMT2ARECQLALDH1A1HPGD
SCHEMBL1738244 0.88 RECQL (0.52) MEN1KMT2ARECQLALDH1A1HPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1784404-B1 PYRROLO[2,3-C]PYRIDINE DERIVATIVES AND PROCESSES FOR THE PREPARATION THEREOF YUHAN CORP (KR) 2011-11-16 EP claimed
US-20110263306-A1 COMPUTER SYSTEM AND PROGRAM NAMCO BANDAI GAMES INC. (JP) 2011-10-27 US claimed