SCHEMBL17378596

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL10041283	0.90	MAPK1 (0.56)	MAPK1HTTKDM4EALDH1A1HPGD
	SCHEMBL6443356	0.87	ESR2 (0.57)	MAPK1HTTKDM4EALDH1A1HPGD
	SCHEMBL3285853	0.87	MAPK1 (0.54)	MAPK1HTTKDM4EALDH1A1HPGD
	SCHEMBL2093959	0.85	CYP2C9 (0.53)	MAPK1KDM4EALDH1A1HPGDPIK3CB
	SCHEMBL12937256	0.84	MAPK1 (0.74)	MAPK1HTTKDM4EALDH1A1HPGD
	SCHEMBL10041284	0.83	MAPK1 (0.53)	MAPK1HTTKDM4EALDH1A1HPGD
	SCHEMBL2091385	0.83	MAPK1 (0.50)	MAPK1HTTKDM4EALDH1A1HPGD
	SCHEMBL16035164	0.82	RPS6KA5 (0.49)	MAPK1HTTKDM4EALDH1A1HPGD
	SCHEMBL12026134	0.82	MAPK1 (0.61)	MAPK1HTTALDH1A1TSHRSLC22A12
	SCHEMBL28574070	0.81	MAPK1 (0.42)	MAPK1HTTKDM4EALDH1A1HPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.