SCHEMBL1738005

SCHEMBL1738005

Cc1c(C)n(Cc2cccc(F)c2)c2c(N3CCc4ccccc4C3)nc(CF)cc12

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 5/20 0.38
KDM4E B2RXH2 4/20 0.38
MAPK1 P28482 2/20 0.38
POLB P06746 1/20 0.38
NR2F2 P24468 1/20 0.38
RAB9A P51151 1/20 0.38
FABP3 P05413 1/20 0.35
TSHR P16473 5/20 0.34
GRIN2D O15399 4/20 0.34
GRIN3B O60391 4/20 0.34
GRIN1 Q05586 4/20 0.34
GRIN2A Q12879 4/20 0.34
GRIN2B Q13224 4/20 0.34
GRIN2C Q14957 4/20 0.34
GRIN3A Q8TCU5 4/20 0.34
HTT P42858 3/20 0.34
CHRM1 P11229 3/20 0.34
ADRA1D P25100 3/20 0.34
ADRA1A P35348 3/20 0.34
ADRA1B P35368 3/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL1737137 0.99 MAPT (0.37) MAPTKDM4EMAPK1POLBNR2F2
SCHEMBL3595156 0.92 GRIN2D (0.42) MAPTKDM4EMAPK1POLBNR2F2
SCHEMBL1739799 0.92 MAPT (0.37) MAPTKDM4EMAPK1POLBNR2F2
Hydrochloric Acid SCHEMBL1736843 0.91 MAPT (0.37) MAPTKDM4EMAPK1POLBNR2F2
SCHEMBL1738725 0.91 MAPT (0.38) MAPTKDM4EMAPK1POLBNR2F2
Hydrochloric Acid SCHEMBL1736624 0.90 MAPT (0.38) MAPTKDM4EMAPK1POLBNR2F2
SCHEMBL1737609 0.90 KDM4E (0.36) MAPTKDM4EMAPK1POLBNR2F2
SCHEMBL1736974 0.90 EHMT2 (0.36) MAPTKDM4EMAPK1POLBNR2F2
Hydrochloric Acid SCHEMBL1737175 0.89 EHMT2 (0.36) MAPTKDM4EMAPK1POLBNR2F2
SCHEMBL1739795 0.89 MAPT (0.35) MAPTKDM4EMAPK1POLBNR2F2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1784404-B1 PYRROLO[2,3-C]PYRIDINE DERIVATIVES AND PROCESSES FOR THE PREPARATION THEREOF YUHAN CORP (KR) 2011-11-16 EP claimed
US-20110263306-A1 COMPUTER SYSTEM AND PROGRAM NAMCO BANDAI GAMES INC. (JP) 2011-10-27 US claimed
EP-1784404-A4 PYRROLO[2,3-C]PYRIDINE DERIVATIVES AND PROCESSES FOR THE PREPARATION THEREOF YUHAN CORP (KR) 2009-09-09 EP claimed
JP-2008511621-A 2008-04-17 JP claimed
EP-1784404-A1 PYRROLO[2,3-C]PYRIDINE DERIVATIVES AND PROCESSES FOR THE PREPARATION THEREOF Yuhan Corporation (KR) 2007-05-16 EP claimed
WO-2006025716-A1 PYRROLO[2,3-C]PYRIDINE DERIVATIVES AND PROCESSES FOR THE PREPARATION THEREOF YUHAN CORPORATION (KR) 2006-03-09 WO claimed