Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 2/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | MAPK14 | Q16539 | 3/20 | 0.34 |
| ▸ | AURKA | O14965 | 1/20 | 0.34 |
| ▸ | ABL1 | P00519 | 1/20 | 0.34 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.34 |
| ▸ | LCK | P06239 | 1/20 | 0.34 |
| ▸ | CSF1R | P07333 | 1/20 | 0.34 |
| ▸ | RET | P07949 | 1/20 | 0.34 |
| ▸ | MET | P08581 | 1/20 | 0.34 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.34 |
| ▸ | PIM1 | P11309 | 1/20 | 0.34 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.34 |
| ▸ | FLT3 | P36888 | 1/20 | 0.34 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.34 |
| ▸ | CDK8 | P49336 | 1/20 | 0.34 |
| ▸ | MAP2K1 | Q02750 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL1736913 | 0.99 | CYP1A2 (0.35) | CYP1A2CYP3A4CYP2C9CYP2C19KMT2A | |
| SCHEMBL1738138 | 0.92 | CYP1A2 (0.35) | CYP1A2CYP3A4CYP2C9CYP2C19KMT2A | |
| SCHEMBL1738232 | 0.91 | CYP1A2 (0.38) | CYP1A2CYP3A4CYP2C9CYP2C19MAPK14 | |
| Hydrochloric Acid SCHEMBL1736170 | 0.91 | CYP1A2 (0.34) | CYP1A2CYP3A4CYP2C9CYP2C19KMT2A | |
| Hydrochloric Acid SCHEMBL1736644 | 0.90 | CYP1A2 (0.38) | CYP1A2CYP3A4CYP2C9CYP2C19MAPK14 | |
| SCHEMBL1737587 | 0.90 | SMN1; SMN2 (0.34) | CYP1A2CYP3A4CYP2C9CYP2C19KMT2A | |
| SCHEMBL1736714 | 0.90 | PDE2A (0.34) | CYP1A2CYP3A4CYP2C9CYP2C19MAPK14 | |
| Hydrochloric Acid SCHEMBL1735390 | 0.89 | SMN1; SMN2 (0.34) | CYP1A2CYP3A4CYP2C9CYP2C19KMT2A | |
| Hydrochloric Acid SCHEMBL1738281 | 0.89 | PDE2A (0.34) | CYP1A2CYP3A4CYP2C9CYP2C19MAPK14 | |
| SCHEMBL1737247 | 0.88 | CYP1A2 (0.38) | CYP1A2CYP3A4CYP2C9CYP2C19MAPK14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1784404-B1 | PYRROLO[2,3-C]PYRIDINE DERIVATIVES AND PROCESSES FOR THE PREPARATION THEREOF | YUHAN CORP (KR) | 2011-11-16 | — | — | EP | claimed |
| US-20110263306-A1 | COMPUTER SYSTEM AND PROGRAM | NAMCO BANDAI GAMES INC. (JP) | 2011-10-27 | — | — | US | claimed |