Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYSLTR1 | Q9Y271 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 6/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | TUBB1 | Q9H4B7 | 2/20 | 0.34 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.34 |
| ▸ | TUBB | P07437 | 1/20 | 0.34 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.34 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.34 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.34 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.34 |
| ▸ | TUBB3 | Q13509 | 1/20 | 0.34 |
| ▸ | TUBB2A | Q13885 | 1/20 | 0.34 |
| ▸ | TUBB8 | Q3ZCM7 | 1/20 | 0.34 |
| ▸ | TUBA3E | Q6PEY2 | 1/20 | 0.34 |
| ▸ | TUBA1A | Q71U36 | 1/20 | 0.34 |
| ▸ | TUBA1C | Q9BQE3 | 1/20 | 0.34 |
| ▸ | TUBB6 | Q9BUF5 | 1/20 | 0.34 |
| ▸ | TUBB2B | Q9BVA1 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL131026 | 0.77 | CYSLTR1 (0.43) | CYSLTR1MAPTTSHRALDH1A1RAB9A | |
| SCHEMBL19722926 | 0.73 | CYSLTR1 (0.44) | CYSLTR1L3MBTL1TDP1RAB9AFFAR1 | |
| SCHEMBL21916268 | 0.72 | CYP1A1 (0.44) | MAPTMEN1KMT2AGAAALDH1A1 | |
| SCHEMBL22369027 | 0.71 | MAOB (0.44) | CYSLTR1MAPTTSHRGAAALDH1A1 | |
| SCHEMBL22457039 | 0.71 | CYSLTR1 (0.44) | CYSLTR1MAPTMEN1KMT2AGAA | |
| SCHEMBL13256249 | 0.70 | NQO1 (0.50) | MAPTMEN1KMT2ATSHRTUBB1 | |
| SCHEMBL14619309 | 0.70 | MAOB (0.61) | MAPTMEN1KMT2ATUBB1TUBB4A | |
| SCHEMBL8280802 | 0.70 | MAOB (0.60) | MAPTMEN1KMT2AGAAALDH1A1 | |
| SCHEMBL19490419 | 0.70 | HRH3 (0.43) | CYSLTR1MEN1KMT2AALDH1A1RAB9A | |
| SCHEMBL27919562 | 0.69 | FYN (0.43) | MAPTTSHRTUBB1TUBB4ATUBB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015199136-A1 | NOVEL PYRROLOPYRIMIDINE COMPOUND OR SALT THEREOF, PHARMACEUTICAL COMPOSITION CONTAINING SAME, ESPECIALLY AGENT FOR PREVENTION AND/OR TREATMENT OF TUMORS ETC BASED ON NAE INHIBITORY EFFECT | 大鵬薬品工業株式会社 | 2015-12-30 | — | — | WO | disclosed |