SCHEMBL17386554

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL5766669	0.91	HPGD (0.40)	HPGDSMN1; SMN2USP2NR1H2NPC1
	SCHEMBL18309958	0.90	USP2 (0.45)	HPGDSMN1; SMN2USP2NR1H2CTSK
	SCHEMBL31387757	0.86	HPGD (0.42)	HPGDSMN1; SMN2USP2NR1H2MEN1
	SCHEMBL2896952	0.86	HPGD (0.42)	HPGDSMN1; SMN2USP2NR1H2MEN1
	SCHEMBL31230945	0.86	HPGD (0.42)	HPGDSMN1; SMN2USP2NR1H2NPC1
	SCHEMBL14377716	0.84	HPGD (0.39)	HPGDSMN1; SMN2USP2NR1H2MEN1
	SCHEMBL22022990	0.83	NR1H2 (0.47)	HPGDSMN1; SMN2USP2NR1H2MEN1
	SCHEMBL25051625	0.83	HPGD (0.42)	HPGDSMN1; SMN2USP2NR1H2MEN1
	SCHEMBL30430792	0.83	HPGD (0.42)	HPGDSMN1; SMN2USP2NR1H2MEN1
	SCHEMBL31141092	0.82	HPGD (0.40)	HPGDSMN1; SMN2USP2NR1H2MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.