SCHEMBL17387428

SCHEMBL17387428

O=C1CC(O)(C(F)(F)F)c2c(C3CCN(c4nc(C(F)(F)F)c(C(=O)O)o4)CC3)n[nH]c2N1

nearest known ligand 0.58

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
▸ LCAT P04180 20/20 0.58

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16648610 0.88 LCAT (0.76) LCAT
SCHEMBL16648515 0.79 LCAT (0.73) LCAT
SCHEMBL16648803 0.79 LCAT (0.71) LCAT
SCHEMBL16648588 0.77 LCAT (0.69) LCAT
SCHEMBL15051805 0.77 LCAT (0.44) LCAT
SCHEMBL17387426 0.75 LCAT (0.63) LCAT
SCHEMBL16648742 0.75 LCAT (0.71) LCAT
SCHEMBL16648673 0.75 LCAT (0.72) LCAT
SCHEMBL16648488 0.74 LCAT (0.72) LCAT
SCHEMBL16648909 0.74 LCAT (0.69) LCAT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2862861-B1 PIPERIDINYLPYRAZOLOPYRIDINE DERIVATIVE DAIICHI SANKYO CO LTD (JP) 2016-01-06 — — EP claimed
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