Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17957113 | 0.93 | JAK2 (0.67) | JAK2JAK1 | |
| SCHEMBL14563474 | 0.92 | JAK2 (0.66) | JAK2JAK1 | |
| SCHEMBL17957104 | 0.91 | JAK2 (0.68) | JAK2JAK1 | |
| SCHEMBL17957103 | 0.91 | JAK2 (0.67) | JAK2JAK1 | |
| SCHEMBL17957100 | 0.91 | JAK2 (0.68) | JAK2JAK1 | |
| SCHEMBL14563783 | 0.90 | JAK2 (0.68) | JAK2JAK1 | |
| SCHEMBL17387467 | 0.90 | JAK2 (0.69) | JAK2JAK1 | |
| SCHEMBL14563463 | 0.90 | JAK2 (0.69) | JAK2JAK1 | |
| SCHEMBL14563414 | 0.89 | JAK2 (0.69) | JAK2JAK1 | |
| SCHEMBL14563583 | 0.89 | JAK2 (0.69) | JAK2JAK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3050882-A1 | PIPERIDIN-4-YL AZETIDINE DERIVATIVES AS JAK1 INHIBITORS | Incyte Holdings Corporation (US) | 2016-08-03 | — | — | EP | claimed |
| EP-2545045-B1 | PIPERIDIN-4-YL AZETIDINE DERIVATIVES AS JAK1 INHIBITORS | INCYTE HOLDINGS CORP (US) | 2016-01-06 | — | — | EP | claimed |
| EP-3050882-A1 | PIPERIDIN-4-YL AZETIDINE DERIVATIVES AS JAK1 INHIBITORS | Incyte Holdings Corporation (US) | 2016-08-03 | — | — | EP | disclosed |
| EP-2545045-B1 | PIPERIDIN-4-YL AZETIDINE DERIVATIVES AS JAK1 INHIBITORS | INCYTE HOLDINGS CORP (US) | 2016-01-06 | — | — | EP | disclosed |