Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSP90AA1 | P07900 | 11/20 | 0.59 |
| ▸ | HSP90AB1 | P08238 | 3/20 | 0.53 |
| ▸ | ALOX5AP | P20292 | 9/20 | 0.44 |
| ▸ | FEN1 | P39748 | 9/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17387517 | 1.00 | HSP90AA1 (0.59) | HSP90AA1HSP90AB1ALOX5APFEN1 | |
| SCHEMBL2510037 | 0.93 | HSP90AA1 (0.59) | HSP90AA1HSP90AB1ALOX5APFEN1 | |
| SCHEMBL12199675 | 0.92 | HSP90AA1 (0.59) | HSP90AA1HSP90AB1ALOX5APFEN1 | |
| SCHEMBL17387523 | 0.90 | HSP90AA1 (0.62) | HSP90AA1HSP90AB1ALOX5APFEN1 | |
| SCHEMBL12199670 | 0.90 | HSP90AA1 (0.61) | HSP90AA1HSP90AB1ALOX5APFEN1 | |
| SCHEMBL2509529 | 0.88 | HSP90AA1 (0.63) | HSP90AA1HSP90AB1ALOX5APFEN1 | |
| SCHEMBL2512968 | 0.88 | HSP90AA1 (0.65) | HSP90AA1HSP90AB1ALOX5APFEN1 | |
| SCHEMBL12199674 | 0.88 | HSP90AA1 (0.55) | HSP90AA1HSP90AB1ALOX5APFEN1 | |
| SCHEMBL3097085 | 0.86 | HSP90AA1 (0.63) | HSP90AA1HSP90AB1ALOX5APFEN1 | |
| SCHEMBL12199676 | 0.86 | HSP90AA1 (0.62) | HSP90AA1HSP90AB1ALOX5APFEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2356110-B1 | QUINAZOLINAMIDE DERIVATIVES | MERCK PATENT GMBH (DE) | 2016-01-06 | — | — | EP | claimed |