SCHEMBL17387604

SCHEMBL17387604

CCN(Cc1cc(C(F)(F)F)ccc1-c1cc(OC)cc([C@@H](C)C(=O)O)c1)C(=O)C1CC1

nearest known ligand 0.57

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
PTGDR2 Q9Y5Y4 20/20 0.57

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17387608 1.00 PTGDR2 (0.57) PTGDR2
SCHEMBL151753 0.90 PTGDR2 (0.56) PTGDR2
SCHEMBL149278 0.90 PTGDR2 (0.56) PTGDR2
SCHEMBL151446 0.90 PTGDR2 (0.56) PTGDR2
SCHEMBL149824 0.88 PTGDR2 (0.53) PTGDR2
SCHEMBL148686 0.83 PTGDR2 (0.72) PTGDR2
SCHEMBL148688 0.83 PTGDR2 (0.72) PTGDR2
SCHEMBL151661 0.83 PTGDR2 (0.72) PTGDR2
SCHEMBL135277 0.83 PTGDR2 (0.51) PTGDR2
SCHEMBL136570 0.83 PTGDR2 (0.51) PTGDR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2257524-B1 N,N-DISUBSTITUTED AMINOALKYLBIPHENYL ANTAGONISTS OF PROSTAGLANDIN D2 RECEPTORS BRICKELL BIOTECH INC (US) 2016-01-06 EP disclosed