Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGDR2 | Q9Y5Y4 | 20/20 | 0.79 |
| ▸ | PTGDR | Q13258 | 4/20 | 0.79 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.79 |
| ▸ | TBXA2R | P21731 | 3/20 | 0.50 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.46 |
| ▸ | PTGIR | P43119 | 2/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL137393 | 0.95 | PTGDR2 (0.88) | PTGDR2PTGDRCYP3A4TBXA2RCYP2C9 | |
| SCHEMBL10324108 | 0.94 | PTGDR2 (0.87) | PTGDR2PTGDRCYP3A4TBXA2RCYP2C9 | |
| SCHEMBL10324111 | 0.94 | PTGDR2 (0.87) | PTGDR2PTGDRCYP3A4TBXA2RCYP2C9 | |
| SCHEMBL137380 | 0.87 | PTGDR2 (0.85) | PTGDR2PTGDRCYP3A4TBXA2RCYP2C9 | |
| SCHEMBL137951 | 0.87 | PTGDR2 (1.00) | PTGDR2PTGDRCYP3A4TBXA2RCYP2C9 | |
| SCHEMBL135143 | 0.86 | PTGDR2 (1.00) | PTGDR2PTGDRCYP3A4TBXA2RCYP2C9 | |
| SCHEMBL135003 | 0.85 | PTGDR2 (0.80) | PTGDR2PTGDRCYP3A4TBXA2RCYP2C9 | |
| SCHEMBL137822 | 0.85 | PTGDR2 (1.00) | PTGDR2PTGDRCYP3A4TBXA2RCYP2C9 | |
| SCHEMBL151860 | 0.84 | PTGDR2 (0.77) | PTGDR2PTGDRCYP3A4TBXA2RCYP2C9 | |
| SCHEMBL136418 | 0.84 | PTGDR2 (0.84) | PTGDR2PTGDRCYP3A4TBXA2RCYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2257524-B1 | N,N-DISUBSTITUTED AMINOALKYLBIPHENYL ANTAGONISTS OF PROSTAGLANDIN D2 RECEPTORS | BRICKELL BIOTECH INC (US) | 2016-01-06 | — | — | EP | disclosed |