Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGDR2 | Q9Y5Y4 | 20/20 | 0.53 |
| ▸ | PTGDR | Q13258 | 3/20 | 0.53 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.53 |
| ▸ | TBXA2R | P21731 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL154253 | 0.94 | PTGDR2 (0.61) | PTGDR2PTGDRCYP3A4TBXA2R | |
| SCHEMBL10324110 | 0.88 | PTGDR2 (0.69) | PTGDR2PTGDRCYP3A4TBXA2R | |
| SCHEMBL153753 | 0.87 | PTGDR2 (0.67) | PTGDR2PTGDRCYP3A4TBXA2R | |
| SCHEMBL154091 | 0.87 | PTGDR2 (0.59) | PTGDR2PTGDRCYP3A4 | |
| SCHEMBL151412 | 0.86 | PTGDR2 (0.68) | PTGDR2PTGDRCYP3A4TBXA2R | |
| SCHEMBL139479 | 0.85 | PTGDR2 (0.58) | PTGDR2PTGDRTBXA2R | |
| SCHEMBL150473 | 0.85 | PTGDR2 (0.68) | PTGDR2PTGDRCYP3A4TBXA2R | |
| SCHEMBL151340 | 0.85 | PTGDR2 (0.58) | PTGDR2PTGDRCYP3A4TBXA2R | |
| SCHEMBL151861 | 0.84 | PTGDR2 (0.54) | PTGDR2PTGDRCYP3A4TBXA2R | |
| SCHEMBL139647 | 0.83 | PTGDR2 (0.55) | PTGDR2PTGDRTBXA2R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2257524-B1 | N,N-DISUBSTITUTED AMINOALKYLBIPHENYL ANTAGONISTS OF PROSTAGLANDIN D2 RECEPTORS | BRICKELL BIOTECH INC (US) | 2016-01-06 | — | — | EP | disclosed |