Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGDR2 | Q9Y5Y4 | 20/20 | 0.56 |
| ▸ | TBXA2R | P21731 | 2/20 | 0.47 |
| ▸ | PTGDR | Q13258 | 2/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.47 |
| ▸ | PTGIR | P43119 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17387630 | 0.93 | PTGDR2 (0.48) | PTGDR2TBXA2RPTGDRCYP3A4CYP2C9 | |
| SCHEMBL139357 | 0.89 | PTGDR2 (0.64) | PTGDR2TBXA2RPTGDRCYP3A4CYP2C9 | |
| SCHEMBL3412584 | 0.88 | PTGDR2 (0.58) | PTGDR2TBXA2RPTGDRCYP3A4CYP2C9 | |
| SCHEMBL136321 | 0.88 | PTGDR2 (0.64) | PTGDR2TBXA2RPTGDRCYP3A4CYP2C9 | |
| SCHEMBL137769 | 0.85 | PTGDR2 (0.66) | PTGDR2TBXA2RPTGDRCYP3A4CYP2C9 | |
| SCHEMBL142884 | 0.85 | PTGDR2 (0.78) | PTGDR2TBXA2RPTGDRCYP3A4CYP2C9 | |
| SCHEMBL137574 | 0.85 | PTGDR2 (0.66) | PTGDR2TBXA2RPTGDRCYP3A4CYP2C9 | |
| SCHEMBL138098 | 0.85 | PTGDR2 (0.67) | PTGDR2TBXA2RPTGDRCYP3A4CYP2C9 | |
| SCHEMBL139710 | 0.84 | PTGDR2 (0.55) | PTGDR2TBXA2RPTGDRCYP3A4CYP2C9 | |
| SCHEMBL152921 | 0.81 | PTGDR2 (0.72) | PTGDR2TBXA2RPTGDRCYP3A4CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2257524-B1 | N,N-DISUBSTITUTED AMINOALKYLBIPHENYL ANTAGONISTS OF PROSTAGLANDIN D2 RECEPTORS | BRICKELL BIOTECH INC (US) | 2016-01-06 | — | — | EP | claimed |