Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 2/20 | 0.42 |
| ▸ | SIGMAR1 | Q99720 | 4/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.39 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.39 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.39 |
| ▸ | LTA4H | P09960 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL621791 | 0.80 | MEN1 (0.42) | GAAMEN1KMT2ASMN1; SMN2ALDH1A1 | |
| SCHEMBL621789 | 0.80 | MEN1 (0.42) | GAAMEN1KMT2ASMN1; SMN2ALDH1A1 | |
| SCHEMBL20952520 | 0.70 | SMN1; SMN2 (0.54) | GAAMEN1KMT2ASMN1; SMN2ALDH1A1 | |
| SCHEMBL622080 | 0.68 | KCNH2 (0.57) | MEN1KMT2ASMN1; SMN2ALDH1A1TSHR | |
| SCHEMBL622082 | 0.68 | KCNH2 (0.57) | MEN1KMT2ASMN1; SMN2ALDH1A1TSHR | |
| SCHEMBL21583731 | 0.68 | SMN1; SMN2 (0.62) | MEN1KMT2ASMN1; SMN2ALDH1A1HPGD | |
| SCHEMBL11999940 | 0.67 | KDM1A (0.45) | SMN1; SMN2ALDH1A1HPGD | |
| SCHEMBL619732 | 0.67 | SLC6A2 (0.50) | KMT2A | |
| SCHEMBL19926744 | 0.67 | SMN1; SMN2 (0.57) | GAAMEN1KMT2ASMN1; SMN2ALDH1A1 | |
| Hydrochloric Acid SCHEMBL2798369 | 0.67 | KDM1A (0.44) | SMN1; SMN2ALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2389376-A1 | NOVEL BICYCLIC ANTIBIOTICS | Basilea Pharmaceutica AG (CH) | 2011-11-30 | — | — | EP | disclosed |
| WO-2010084152-A1 | NOVEL BICYCLIC ANTIBIOTICS | BASILEA PHARMACEUTICA AG (CH) | 2010-07-29 | — | — | WO | disclosed |