Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CETP | P11597 | 5/20 | 0.56 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.47 |
| ▸ | CDC25A | P30304 | 1/20 | 0.47 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.47 |
| ▸ | MAPKAPK2 | P49137 | 1/20 | 0.42 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.38 |
| ▸ | USP2 | O75604 | 2/20 | 0.38 |
| ▸ | TP53 | P04637 | 2/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.38 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | SULT1E1 | P49888 | 1/20 | 0.35 |
| ▸ | PIK3CA | P42336 | 3/20 | 0.33 |
| ▸ | PIK3CG | P48736 | 3/20 | 0.33 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21858867 | 0.85 | CETP (0.59) | CETPPTPN1CDC25ADUSP3MAPKAPK2 | |
| SCHEMBL2230005 | 0.83 | CETP (0.56) | CETPPTPN1CDC25ADUSP3MAPKAPK2 | |
| SCHEMBL13455164 | 0.83 | CETP (0.56) | CETPPTPN1CDC25ADUSP3MAPKAPK2 | |
| SCHEMBL2920102 | 0.83 | CETP (0.56) | CETPPTPN1CDC25ADUSP3MAPKAPK2 | |
| SCHEMBL11937173 | 0.81 | CETP (0.54) | CETPPTPN1CDC25ADUSP3MAPKAPK2 | |
| SCHEMBL2229971 | 0.81 | CETP (0.54) | CETPPTPN1CDC25ADUSP3MAPKAPK2 | |
| SCHEMBL20077284 | 0.79 | POLA1 (0.47) | CETPPTPN1CDC25ADUSP3 | |
| SCHEMBL13850067 | 0.73 | CETP (0.39) | CETPPTPN1CDC25ADUSP3MAPKAPK2 | |
| SCHEMBL4604284 | 0.72 | PTPN1 (0.52) | CETPPTPN1CDC25ADUSP3MAPKAPK2 | |
| SCHEMBL6791669 | 0.72 | CETP (0.45) | CETPPTPN1CDC25ADUSP3MAPKAPK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3164377-A1 | PRINS REACTION ON HINDERED SUBSTRATES | Firmenich SA (CH) | 2017-05-10 | — | — | EP | disclosed |
| WO-2016001286-A1 | PRINS REACTION ON HINDERED SUBSTRATES | FIRMENICH SA (CH) | 2016-01-07 | — | — | WO | disclosed |