Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CD | O00329 | 18/20 | 0.43 |
| ▸ | PIK3CG | P48736 | 2/20 | 0.41 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.37 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17397272 | 0.94 | PIK3CD (0.46) | PIK3CDPIK3CGPIK3CAPIK3CB | |
| SCHEMBL17397138 | 0.91 | PIK3CD (0.46) | PIK3CDPIK3CGPIK3CAPIK3CB | |
| SCHEMBL17397140 | 0.85 | PIK3CD (0.46) | PIK3CDPIK3CGPIK3CAPIK3CB | |
| SCHEMBL17397141 | 0.84 | PIK3CD (0.52) | PIK3CDPIK3CGPIK3CAPIK3CB | |
| SCHEMBL17397169 | 0.83 | PIK3CD (0.44) | PIK3CDPIK3CGPIK3CAPIK3CB | |
| SCHEMBL17397162 | 0.81 | PIK3CD (0.54) | PIK3CDPIK3CGPIK3CAPIK3CB | |
| SCHEMBL17401132 | 0.81 | PIK3CD (0.54) | PIK3CDPIK3CGPIK3CAPIK3CB | |
| SCHEMBL17401163 | 0.81 | PIK3CD (0.54) | PIK3CDPIK3CGPIK3CAPIK3CB | |
| SCHEMBL17397103 | 0.80 | PIK3CD (0.53) | PIK3CDPIK3CAPIK3CB | |
| SCHEMBL17397134 | 0.79 | PIK3CD (0.41) | PIK3CDPIK3CGPIK3CAPIK3CB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3164400-A1 | QUINOLIZINONE DERIVATIVES AS PI3K INHIBITORS | Lupin Limited (IN) | 2017-05-10 | — | — | EP | claimed |
| WO-2016001855-A1 | QUINOLIZINONE DERIVATIVES AS PI3K INHIBITORS | LUPIN LIMITED (IN) | 2016-01-07 | — | — | WO | claimed |
| EP-3164400-A1 | QUINOLIZINONE DERIVATIVES AS PI3K INHIBITORS | Lupin Limited (IN) | 2017-05-10 | — | — | EP | disclosed |
| WO-2016001855-A1 | QUINOLIZINONE DERIVATIVES AS PI3K INHIBITORS | LUPIN LIMITED (IN) | 2016-01-07 | — | — | WO | disclosed |