Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CD | O00329 | 18/20 | 0.67 |
| ▸ | PIK3CA | P42336 | 10/20 | 0.51 |
| ▸ | PIK3CB | P42338 | 5/20 | 0.51 |
| ▸ | PIK3CG | P48736 | 3/20 | 0.42 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.37 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17397218 | 0.94 | PIK3CD (0.58) | PIK3CDPIK3CAPIK3CBPIK3CG | |
| SCHEMBL17397182 | 0.86 | PIK3CD (0.66) | PIK3CDPIK3CAPIK3CBPIK3CG | |
| SCHEMBL17397098 | 0.85 | PIK3CD (0.57) | PIK3CDPIK3CAPIK3CBPIK3CG | |
| SCHEMBL17397153 | 0.84 | PIK3CD (0.68) | PIK3CDPIK3CAPIK3CBPIK3CG | |
| SCHEMBL17397151 | 0.83 | PIK3CD (0.54) | PIK3CDPIK3CAPIK3CBPIK3CG | |
| SCHEMBL18988646 | 0.82 | PIK3CD (0.56) | PIK3CDPIK3CAPIK3CBPIK3CGADORA2A | |
| SCHEMBL17397143 | 0.81 | PIK3CD (0.46) | PIK3CDPIK3CAPIK3CBPIK3CG | |
| SCHEMBL17397117 | 0.81 | PIK3CD (0.64) | PIK3CDPIK3CAPIK3CBPIK3CG | |
| SCHEMBL17397259 | 0.80 | PIK3CA (0.65) | PIK3CDPIK3CAPIK3CBPIK3CG | |
| SCHEMBL17397071 | 0.80 | PIK3CD (0.46) | PIK3CDPIK3CAPIK3CBPIK3CG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3164400-A1 | QUINOLIZINONE DERIVATIVES AS PI3K INHIBITORS | Lupin Limited (IN) | 2017-05-10 | — | — | EP | claimed |
| WO-2016001855-A1 | QUINOLIZINONE DERIVATIVES AS PI3K INHIBITORS | LUPIN LIMITED (IN) | 2016-01-07 | — | — | WO | claimed |
| EP-3164400-A1 | QUINOLIZINONE DERIVATIVES AS PI3K INHIBITORS | Lupin Limited (IN) | 2017-05-10 | — | — | EP | disclosed |
| WO-2016001855-A1 | QUINOLIZINONE DERIVATIVES AS PI3K INHIBITORS | LUPIN LIMITED (IN) | 2016-01-07 | — | — | WO | disclosed |