Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRKCQ | Q04759 | 15/20 | 1.00 |
| ▸ | PRKD3 | O94806 | 10/20 | 1.00 |
| ▸ | PRKCG | P05129 | 10/20 | 1.00 |
| ▸ | PRKCZ | Q05513 | 10/20 | 1.00 |
| ▸ | PRKCD | Q05655 | 10/20 | 1.00 |
| ▸ | PRKCB | P05771 | 9/20 | 1.00 |
| ▸ | PRKCA | P17252 | 9/20 | 1.00 |
| ▸ | PRKCH | P24723 | 9/20 | 1.00 |
| ▸ | PRKCI | P41743 | 9/20 | 1.00 |
| ▸ | PRKCE | Q02156 | 9/20 | 1.00 |
| ▸ | PRKD1 | Q15139 | 9/20 | 1.00 |
| ▸ | ROCK2 | O75116 | 7/20 | 1.00 |
| ▸ | EGFR | P00533 | 7/20 | 1.00 |
| ▸ | PRKACA | P17612 | 7/20 | 1.00 |
| ▸ | PRKACG | P22612 | 6/20 | 1.00 |
| ▸ | PRKACB | P22694 | 6/20 | 1.00 |
| ▸ | SRC | P12931 | 4/20 | 1.00 |
| ▸ | CHEK1 | O14757 | 3/20 | 1.00 |
| ▸ | MAPK1 | P28482 | 3/20 | 1.00 |
| ▸ | KDR | P35968 | 3/20 | 1.00 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Staurosporine SCHEMBL12245439 | 1.00 | PRKCQ (1.00) | PRKCQPRKD3PRKCGPRKCZPRKCD | |
| Staurosporine SCHEMBL8157 | 1.00 | PRKCQ (1.00) | PRKCQPRKD3PRKCGPRKCZPRKCD | |
| Staurosporine SCHEMBL8156 | 1.00 | PRKCQ (1.00) | PRKCQPRKD3PRKCGPRKCZPRKCD | |
| Staurosporine SCHEMBL14264595 | 1.00 | PRKCQ (1.00) | PRKCQPRKD3PRKCGPRKCZPRKCD | |
| Staurosporine SCHEMBL23768489 | 1.00 | PRKCQ (1.00) | PRKCQPRKD3PRKCGPRKCZPRKCD | |
| Staurosporine SCHEMBL13659665 | 1.00 | PRKCQ (1.00) | PRKCQPRKD3PRKCGPRKCZPRKCD | |
| Staurosporine SCHEMBL23793206 | 1.00 | PRKCQ (1.00) | PRKCQPRKD3PRKCGPRKCZPRKCD | |
| SCHEMBL24393902 | 1.00 | PRKCQ (1.00) | PRKCQPRKD3PRKCGPRKCZPRKCD | |
| Staurosporine SCHEMBL21312855 | 1.00 | PRKCQ (1.00) | PRKCQPRKD3PRKCGPRKCZPRKCD | |
| Staurosporine SCHEMBL14554228 | 1.00 | PRKCQ (1.00) | PRKCQPRKD3PRKCGPRKCZPRKCD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117203211-A | Imidazo thiazole derivative, preparation method and application thereof | 中国海洋大学 | 2023-12-08 | — | — | CN | disclosed |
| CN-106432246-B | Heteroaromatic compounds and their use in medicine | 广东东阳光药业有限公司 | 2020-07-07 | — | — | CN | disclosed |
| WO-2016000615-A1 | HETEROARYL COMPOUNDS AND PHARMACEUTICAL APPLICATIONS THEREOF | SUNSHINE LAKE PHARMA CO., LTD. (CN) | 2016-01-07 | — | — | WO | disclosed |