Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDR | P35968 | 1/20 | 0.51 |
| ▸ | FNTA | P49354 | 1/20 | 0.46 |
| ▸ | FNTB | P49356 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 4/20 | 0.45 |
| ▸ | RAB9A | P51151 | 4/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.45 |
| ▸ | TP53 | P04637 | 2/20 | 0.45 |
| ▸ | GRM4 | Q14833 | 2/20 | 0.45 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.45 |
| ▸ | MALT1 | Q9UDY8 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | GRM5 | P41594 | 1/20 | 0.44 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.44 |
| ▸ | RELA | Q04206 | 1/20 | 0.44 |
| ▸ | ACKR3 | P25106 | 2/20 | 0.44 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 3/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17399084 | 1.00 | KDR (0.51) | KDRFNTAFNTBNPC1RAB9A | |
| SCHEMBL16017725 | 1.00 | KDR (0.51) | KDRFNTAFNTBNPC1RAB9A | |
| SCHEMBL16007186 | 0.88 | KDR (0.54) | KDRFNTAFNTBNPC1RAB9A | |
| SCHEMBL16007568 | 0.87 | KDR (0.50) | KDRNPC1RAB9ASMN1; SMN2TP53 | |
| SCHEMBL16007567 | 0.87 | KDR (0.50) | KDRNPC1RAB9ASMN1; SMN2TP53 | |
| SCHEMBL16007598 | 0.87 | KDR (0.50) | KDRNPC1RAB9ASMN1; SMN2TP53 | |
| SCHEMBL16007807 | 0.85 | ACKR3 (0.53) | KDRNPC1RAB9ASMN1; SMN2ACKR3 | |
| SCHEMBL16007826 | 0.85 | ACKR3 (0.53) | KDRNPC1RAB9ASMN1; SMN2ACKR3 | |
| SCHEMBL16007510 | 0.85 | ACKR3 (0.53) | KDRNPC1RAB9ASMN1; SMN2ACKR3 | |
| SCHEMBL16017749 | 0.84 | ANO1 (0.52) | KDRFNTAFNTBMALT1ACKR3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9227955-B2 | Compound having angiogenesis inhibitory activity, method for preparing same, and pharmaceutical composition comprising same | BORYUNG PHARMACEUTICAL CO., LTD. (KR) | 2016-01-05 | — | — | US | disclosed |