Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5AP | P20292 | 19/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | GSK3B | P49841 | 1/20 | 0.36 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17399661 | 0.83 | ALOX5AP (0.37) | ALOX5APCYP2C9CYP2D6 | |
| SCHEMBL15166464 | 0.75 | ALOX5AP (0.47) | ALOX5APCYP2C9CYP2D6 | |
| SCHEMBL15166465 | 0.75 | ALOX5AP (0.37) | ALOX5APCYP2C9CYP2D6 | |
| SCHEMBL12005308 | 0.73 | ALOX5AP (0.46) | ALOX5APCYP2C9CYP2D6 | |
| SCHEMBL18220924 | 0.73 | ALOX5AP (0.42) | ALOX5APCYP2C9CYP2D6 | |
| SCHEMBL15166476 | 0.72 | ALOX5AP (0.55) | ALOX5APCYP2C9CYP2D6 | |
| SCHEMBL15166463 | 0.71 | ALOX5AP (0.46) | ALOX5APCYP2C9CYP2D6 | |
| SCHEMBL15166490 | 0.70 | ALOX5AP (0.40) | ALOX5APCYP2C9CYP2D6 | |
| SCHEMBL15166467 | 0.67 | ALOX5AP (0.47) | ALOX5APCYP2C9GSK3BDYRK1ACYP2D6 | |
| SCHEMBL670103 | 0.67 | ALOX5AP (0.65) | ALOX5APCYP2C9CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2606045-B1 | OXADIAZOLE INHIBITORS OF LEUKOTRIENE PRODUCTION | BOEHRINGER INGELHEIM INT (DE) | 2016-01-06 | — | — | EP | disclosed |