Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGDR2 | Q9Y5Y4 | 9/20 | 0.52 |
| ▸ | CETP | P11597 | 11/20 | 0.49 |
| ▸ | TBXA2R | P21731 | 4/20 | 0.46 |
| ▸ | PTGDR | Q13258 | 4/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.43 |
| ▸ | PTGIR | P43119 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL154594 | 0.85 | PTGDR2 (0.72) | PTGDR2CETPTBXA2RPTGDRCYP3A4 | |
| SCHEMBL150573 | 0.82 | CETP (0.53) | PTGDR2CETPTBXA2RPTGDRCYP3A4 | |
| SCHEMBL152863 | 0.81 | CETP (0.57) | PTGDR2CETPTBXA2RPTGDRCYP3A4 | |
| SCHEMBL150422 | 0.79 | PTGDR2 (0.68) | PTGDR2CETPTBXA2RPTGDRCYP3A4 | |
| SCHEMBL153294 | 0.78 | PTGDR2 (0.75) | PTGDR2CETPTBXA2RPTGDRCYP3A4 | |
| SCHEMBL152276 | 0.76 | CETP (0.52) | PTGDR2CETPTBXA2RPTGDR | |
| SCHEMBL150483 | 0.76 | PTGDR2 (0.72) | PTGDR2CETPTBXA2RPTGDRCYP3A4 | |
| SCHEMBL137108 | 0.75 | PTGDR2 (0.56) | PTGDR2CETPTBXA2RPTGDRCYP3A4 | |
| SCHEMBL151192 | 0.74 | CETP (0.56) | PTGDR2CETPTBXA2RPTGDRCYP3A4 | |
| SCHEMBL153972 | 0.73 | CETP (0.61) | PTGDR2CETPTBXA2RPTGDRCYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2257524-B1 | N,N-DISUBSTITUTED AMINOALKYLBIPHENYL ANTAGONISTS OF PROSTAGLANDIN D2 RECEPTORS | BRICKELL BIOTECH INC (US) | 2016-01-06 | — | — | EP | disclosed |