Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | RECQL | P46063 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 3/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | MLYCD | O95822 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.33 |
| ▸ | LTA4H | P09960 | 1/20 | 0.33 |
| ▸ | STING1 | Q86WV6 | 1/20 | 0.33 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.32 |
| ▸ | TLR2 | O60603 | 1/20 | 0.31 |
| ▸ | TLR1 | Q15399 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19478676 | 1.00 | KDM4E (0.36) | KDM4ELMNARECQLTDP1MEN1 | |
| SCHEMBL46884 | 0.90 | KDM4E (0.39) | KDM4ELMNARECQLTDP1MEN1 | |
| SCHEMBL3624896 | 0.90 | KDM4E (0.37) | KDM4ETDP1MEN1KMT2AMLYCD | |
| SCHEMBL26689416 | 0.86 | TLR2 (0.38) | KDM4ELMNATDP1MEN1KMT2A | |
| SCHEMBL27420943 | 0.86 | TLR2 (0.38) | KDM4ELMNATDP1MEN1KMT2A | |
| SCHEMBL17229457 | 0.86 | TLR2 (0.38) | KDM4ELMNATDP1MEN1KMT2A | |
| SCHEMBL31231100 | 0.86 | TLR2 (0.38) | KDM4ELMNATDP1MEN1KMT2A | |
| SCHEMBL19164207 | 0.84 | TLR2 (0.36) | KDM4ETDP1MEN1KMT2AMLYCD | |
| SCHEMBL16086532 | 0.83 | TSHR (0.44) | KDM4ELMNARECQLMEN1KMT2A | |
| SCHEMBL24668232 | 0.83 | STING1 (0.37) | MLYCDALDH1A1STING1EPHX2TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20160000933-A1 | CONJUGATED BIOLOGICAL MOLECULES AND THEIR PREPARATION | POLUKHTIN ANDREI (US) | 2016-01-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160000933-A1 | CONJUGATED BIOLOGICAL MOLECULES AND THEIR PREPARATION | FCGRT, F13B, EPCAM | KDM4E 4629/4885LMNA 4690/4885RECQL 4352/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.