Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16199 | 0.91 | GCK (0.45) | GCKGCKR | |
| SCHEMBL17401 | 0.88 | GCK (0.47) | GCKGCKR | |
| SCHEMBL17564 | 0.88 | GCKR (0.41) | GCKGCKR | |
| SCHEMBL19590 | 0.86 | GCK (0.45) | GCKGCKR | |
| SCHEMBL16797 | 0.85 | GCKR (0.63) | GCKGCKR | |
| SCHEMBL18096 | 0.82 | GCKR (0.51) | GCKGCKR | |
| SCHEMBL12090145 | 0.82 | GCK (0.36) | GCKGCKR | |
| SCHEMBL16569 | 0.81 | GCK (0.55) | GCKGCKR | |
| SCHEMBL16638 | 0.80 | GCKR (0.58) | GCKGCKR | |
| SCHEMBL12090183 | 0.80 | GCK (0.37) | GCKGCKR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2609081-A1 | SULFONYLPIPERAZINE DERIVATIVES THAT INTERACT WITH GLUCOKINASE REGULATORY PROTEIN FOR THE TREATMENT OF DIABETES | Amgen Inc. (US) | 2013-07-03 | — | — | EP | claimed |
| WO-2012027261-A1 | SULFONYLPIPERAZINE DERIVATIVES THAT INTERACT WITH GLUCOKINASE REGULATORY PROTEIN FOR THE TREATMENT OF DIABETES | AMGEN INC. (US) | 2012-03-01 | — | — | WO | claimed |