Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA2A | P29274 | 5/20 | 0.66 |
| ▸ | AHCY | P23526 | 1/20 | 0.66 |
| ▸ | ADORA1 | P30542 | 3/20 | 0.64 |
| ▸ | ADA | P00813 | 4/20 | 0.62 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.62 |
| ▸ | PDE2A | O00408 | 3/20 | 0.62 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.62 |
| ▸ | PDE4A | P27815 | 1/20 | 0.62 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.62 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.62 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.62 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.62 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.62 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.62 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.62 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.62 |
| ▸ | TSHR | P16473 | 1/20 | 0.62 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.62 |
| ▸ | LMNA | P02545 | 1/20 | 0.61 |
| ▸ | BLM | P54132 | 1/20 | 0.61 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13394190 | 0.90 | ADORA2A (0.72) | ADORA2AAHCYADORA1ADACYP3A4 | |
| SCHEMBL11253038 | 0.86 | ADORA2A (0.47) | ADORA2AAHCYADORA1ADACYP3A4 | |
| SCHEMBL8186532 | 0.85 | ADORA2A (0.59) | ADORA2AAHCYADORA1ADACYP3A4 | |
| SCHEMBL8194808 | 0.85 | ADORA2A (0.59) | ADORA2AAHCYADORA1ADACYP3A4 | |
| SCHEMBL8193948 | 0.85 | ADORA2A (0.59) | ADORA2AAHCYADORA1ADACYP3A4 | |
| SCHEMBL8186713 | 0.85 | ADORA2A (0.59) | ADORA2AAHCYADORA1ADACYP3A4 | |
| SCHEMBL8220260 | 0.85 | ADORA2A (0.59) | ADORA2AAHCYADORA1ADACYP3A4 | |
| SCHEMBL14963614 | 0.84 | ADORA2A (0.76) | ADORA2AAHCYADORA1CYP3A4ALDH1A1 | |
| SCHEMBL13394189 | 0.84 | ADORA2A (0.76) | ADORA2AAHCYADORA1CYP3A4ALDH1A1 | |
| SCHEMBL8217400 | 0.84 | CYP3A4 (0.60) | ADORA2AADORA1ADACYP3A4PDE2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 36 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12280057-B2 | Vasoactive topical compound to affect tissue blood flow, reduce tissue necrosis and promote healing | SOUTH DAKOTA BOARD OF REGENTS (US) | 2025-04-22 | — | — | US | claimed |
| CN-104725628-B | A kind of single functionalization branched polyethylene glycol, preparation method and its bio-related substance containing degradable group | 厦门赛诺邦格生物科技股份有限公司 | 2018-04-17 | — | — | CN | claimed |
| US-7507707-B2 | Methods of inducing ovulation using a non-polypeptide camp level modulator | LABORATOIRES SERONO SA (CH) | 2009-03-24 | — | — | US | claimed |
| US-12280057-B2 | Vasoactive topical compound to affect tissue blood flow, reduce tissue necrosis and promote healing | SOUTH DAKOTA BOARD OF REGENTS (US) | 2025-04-22 | — | — | US | disclosed |
| US-20240052418-A1 | METHOD FOR PREDICTING A SUBJECT'S RESPONSE TO SLC MODULATOR THERAPY | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2024-02-15 | — | — | US | disclosed |
| US-11814681-B2 | Method for predicting a subjects response to SLC modulator therapy | THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK (US) | 2023-11-14 | — | — | US | disclosed |
| US-20210254158-A1 | METHOD FOR PREDICTING A SUBJECTS RESPONSE TO SLC MODULATOR THERAPY | RESEARCH FOUNDATION FOR MENTAL HYGIENE, INC. | 2021-08-19 | — | — | US | disclosed |
| US-11041207-B2 | Method for predicting a subject's response to valproic acid therapy | THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK (US) | 2021-06-22 | — | — | US | disclosed |
| CN-112166124-A | Antagonistic CD73 antibodies | 勃林格殷格翰国际有限公司 | 2021-01-01 | — | — | CN | disclosed |
| EP-3207048-A1 | COMPOSITIONS AND METHODS OF TREATING MUSCULAR DYSTROPHY | The Broad Institute, Inc. (US) | 2017-08-23 | — | — | EP | disclosed |
| US-20170224758-A1 | COMPOSITIONS AND METHODS OF TREATING MUSCULAR DYSTROPHY | THE BROAD INSTITUTE, INC. (US) | 2017-08-10 | — | — | US | disclosed |
| US-5641763-A | N-phosphonylmethoxyalkyl derivatives of pyrimdine and purine bases and a therapeutical composition therefrom with antiviral activity | INSTITUTE OF ORGANIC CHEMISTRY AND BIOCHEMISTRY OF THE ACADEMY OF SCIENCES OF THE CZECH REPUBLIC (CZ) | 1997-06-24 | — | — | US | disclosed |
| EP-0633772-A1 | MEDICAMENT AGAINST CARDIAC CIRCULATORY DISEASES | Max-Planck-Gesellschaft zur Förderung der Wissenschaften e.V. (DE) | 1995-01-18 | — | — | EP | disclosed |
| WO-1993019742-A1 | MEDICAMENT AGAINST CARDIAC CIRCULATORY DISEASES | MAX-PLANCK-Gesellschaft zur Förderung der Wissenschaften e.V. (DE) | 1993-10-14 | — | — | WO | disclosed |
| US-5142051-A | Viricides special for mutants of herpes viruses | CESKOSLOVENSKA AKADEMIE VED (CS) | 1992-08-25 | — | — | US | disclosed |
| EP-0227844-B1 | ANTIVIRAL DRUG | TEIJIN LIMITED (JP) | 1992-05-13 | — | — | EP | disclosed |
| EP-0253412-B1 | N-PHOSPHONYLMETHOXYALKYL DERIVATIVES OF PYRIMIDINE AND PURINE BASES, METHODS FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS THEREFROM WITH ANTIVIRAL ACTIVITY | Ceskoslovenska akademie ved (CS) | 1990-10-31 | — | — | EP | disclosed |
| US-4868162-A | 5-HALO-2*-DEOXYURIDINE DERIVATIVE | TEIJIN LIMITED (JP) | 1989-09-19 | — | — | US | disclosed |
| EP-0253412-A2 | N-Phosphonylmethoxyalkyl derivatives of pyrimidine and purine bases, methods for their preparation and pharmaceutical compositions therefrom with antiviral activity | Ceskoslovenska akademie ved (CS) | 1988-01-20 | — | — | EP | disclosed |
| EP-0227844-A1 | ANTIVIRAL DRUG | TEIJIN LIMITED (JP) | 1987-07-08 | — | — | EP | disclosed |