SCHEMBL1740530

SCHEMBL1740530

CC(O)CCCCCCCn1cnc2c(N)ncnc21

nearest known ligand 0.67

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ADORA2A P29274 8/20 0.67
ADORA1 P30542 4/20 0.67
ADORA2B P29275 1/20 0.59
ADCY5 O95622 3/20 0.59
ADA P00813 4/20 0.55
PDE2A O00408 3/20 0.55
CYP3A4 P08684 2/20 0.55
ALDH1A1 P00352 2/20 0.55
PDE4A P27815 1/20 0.55
PDE4B Q07343 1/20 0.55
PDE4C Q08493 1/20 0.55
PDE4D Q08499 1/20 0.55
KDM4E B2RXH2 1/20 0.55
CYP1A2 P05177 1/20 0.55
ALOX15 P16050 1/20 0.55
SMN1; SMN2 Q16637 1/20 0.55
HSD17B10 Q99714 1/20 0.55
TSHR P16473 1/20 0.55
HIF1A Q16665 1/20 0.55
PI4KA P42356 1/20 0.55

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16526337 0.88 ADORA2A (0.69) ADORA2AADORA1ADORA2BADCY5ALDH1A1
SCHEMBL2152703 0.84 ADORA2A (0.64) ADORA2AADORA1ADORA2BADCY5ALDH1A1
SCHEMBL23513431 0.83 ADORA2A (0.71) ADORA2AADORA1ADORA2BADCY5ALDH1A1
SCHEMBL9484927 0.82 ADORA2A (0.88) ADORA2AADORA1ADORA2BADCY5ALDH1A1
SCHEMBL21469779 0.82 ADORA2A (0.88) ADORA2AADORA1ADORA2BADCY5ALDH1A1
SCHEMBL23228230 0.82 ADORA2A (0.88) ADORA2AADORA1ADORA2BADCY5ALDH1A1
SCHEMBL1741560 0.82 ADORA2A (0.88) ADORA2AADORA1ADORA2BADCY5ALDH1A1
SCHEMBL8467390 0.82 ADORA2A (0.88) ADORA2AADORA1ADORA2BADCY5ALDH1A1
SCHEMBL6045563 0.82 ADORA2A (0.61) ADORA2AADORA1ADORA2BADCY5ALDH1A1
SCHEMBL6029043 0.81 ADORA2A (0.63) ADORA2AADORA1ADORA2BADCY5ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2389436-A2 STEM CELL CULTURE METHODS ITI Scotland Limited (GB) 2011-11-30 EP disclosed
US-20110257911-A1 SYSTEMS AND METHODS FOR DETECTING CHANGES IN ENERGY USAGE IN A BUILDING JOHNSON CONTROLS TECHNOLOGY COMPANY 2011-10-20 US disclosed
WO-2010084300-A2 STEM CELL CULTURE METHODS ITI SCOTLAND LIMITED (GB) 2010-07-29 WO disclosed