SCHEMBL1740714

SCHEMBL1740714

O=C(O)CCC(NC(=O)NC(CCCCNC(=O)CCCCCCCCCCNCCc1nccn1CC(=O)O)C(=O)O)C(=O)O

nearest known ligand 0.50

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
FOLH1 Q04609 20/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2496593 0.91 FOLH1 (0.48) FOLH1
SCHEMBL17997541 0.86 FOLH1 (0.52) FOLH1
SCHEMBL15512642 0.86 FOLH1 (0.52) FOLH1
SCHEMBL2794828 0.86 FOLH1 (0.52) FOLH1
SCHEMBL1740716 0.85 FOLH1 (0.49) FOLH1
SCHEMBL17961045 0.84 FOLH1 (0.58) FOLH1
SCHEMBL18030071 0.83 FOLH1 (0.54) FOLH1
SCHEMBL11930707 0.82 FOLH1 (0.49) FOLH1
SCHEMBL11930760 0.81 FOLH1 (0.52) FOLH1
SCHEMBL18030072 0.81 FOLH1 (0.50) FOLH1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2389361-A2 TECHNETIUM- AND RHENIUM-BIS(HETEROARYL) COMPLEXES AND METHODS OF USE THEREOF FOR INHIBITING PSMA Molecular Insight Pharmaceuticals, Inc. (US) 2011-11-30 EP disclosed