Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDR | P35968 | 18/20 | 0.82 |
| ▸ | PDGFRB | P09619 | 13/20 | 0.82 |
| ▸ | GRM5 | P41594 | 2/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17409459 | 0.90 | KDR (1.00) | KDRPDGFRB | |
| SCHEMBL17409494 | 0.87 | KDR (0.76) | KDRPDGFRBGRM5 | |
| SCHEMBL17409470 | 0.86 | KDR (1.00) | KDRPDGFRB | |
| SCHEMBL17409475 | 0.83 | KDR (1.00) | KDRPDGFRBGRM5 | |
| SCHEMBL17409482 | 0.83 | KDR (1.00) | KDRPDGFRB | |
| SCHEMBL17409493 | 0.80 | KDR (1.00) | KDRPDGFRB | |
| SCHEMBL17409457 | 0.79 | KDR (1.00) | KDRPDGFRB | |
| SCHEMBL17409450 | 0.78 | KDR (0.68) | KDRPDGFRB | |
| SCHEMBL17409473 | 0.76 | KDR (1.00) | KDRPDGFRB | |
| SCHEMBL17409485 | 0.76 | KDR (1.00) | KDRPDGFRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9233968-B1 | Kinase inhibitors | ALLERGAN, INC. (US) | 2016-01-12 | — | — | US | disclosed |
| US-9233968-B1 | Kinase inhibitors | ALLERGAN, INC. (US) | 2016-01-12 | — | — | US | disclosed |