Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17409767 | 0.96 | MAPK3 (0.88) | MAPK3EGFR | |
| SCHEMBL15938466 | 0.93 | MAPK3 (1.00) | MAPK3EGFR | |
| SCHEMBL15938345 | 0.92 | MAPK3 (1.00) | MAPK3EGFR | |
| SCHEMBL15938170 | 0.89 | MAPK3 (1.00) | MAPK3EGFR | |
| SCHEMBL15938343 | 0.85 | MAPK3 (1.00) | MAPK3EGFR | |
| SCHEMBL15938730 | 0.84 | MAPK3 (1.00) | MAPK3EGFR | |
| SCHEMBL15938831 | 0.84 | MAPK3 (0.83) | MAPK3EGFR | |
| SCHEMBL15948597 | 0.83 | MAPK3 (0.83) | MAPK3EGFR | |
| SCHEMBL17102721 | 0.83 | MAPK3 (0.80) | MAPK3EGFR | |
| SCHEMBL15938541 | 0.83 | MAPK3 (0.84) | MAPK3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9561228-B2 | ERK inhibitors and uses thereof | CELGENE AVILOMICS RESEARCH, INC. (US) | 2017-02-07 | — | — | US | disclosed |
| US-20160002176-A1 | ERK INHIBITORS AND USES THEREOF | CELGENE AVILOMICS RESEARCH, INC. (US) | 2016-01-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160002176-A1 | ERK INHIBITORS AND USES THEREOF | MAPK1, MAPK3, MAP4K2 | MAPK3 2/4885EGFR 384/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.