SCHEMBL1741012

SCHEMBL1741012

NNC1=NCCC1

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11016214 0.92
SCHEMBL11010223 0.90
SCHEMBL19957455 0.72
SCHEMBL10144664 0.72
Hydrochloric Acid SCHEMBL8327181 0.70
SCHEMBL7639495 0.69
SCHEMBL15182171 0.69
SCHEMBL8519306 0.67
SCHEMBL10884472 0.67 CYP2D6 (0.71)
SCHEMBL10143141 0.67

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 67 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4550169-A ANTITUMOR AND ANTICARCINOGENIC AGENTS AMERICAN CYANAMID COMPANY (US) 1985-10-29 US claimed
EP-2254600-B1 NOVEL COMPOSITIONS AND USES THEREOF BIOSUSPENSIONS LTD (GB) 2017-05-17 EP disclosed
US-9254264-B2 Compositions and uses thereof BIOSUSPENSIONS LIMITED (GB) 2016-02-09 US disclosed
US-8470873-B2 Vitamin E succinate stabilized pharmaceutical compositions, methods for the preparation and the use thereof MAST THERAPEUTICS, INC. (US) 2013-06-25 US disclosed
EP-2387991-A1 Vitamin E succinate stabilized pharmaceutical compositions, methods for the preparation and the use thereof Adventrx Pharmaceuticals, Inc. (US) 2011-11-23 EP disclosed
US-8041772-B2 Autonomic sensor network ecosystem INTERNATIONAL BUSINESS MACHINES CORPORATION (US) 2011-10-18 US disclosed
US-20110117019-A1 Novel Compositions and Uses Thereof BIOSUSPENSIONS LIMITED (GB) 2011-05-19 US disclosed
EP-2254600-A1 NOVEL COMPOSITIONS AND USES THEREOF Biosuspensions Limited (GB) 2010-12-01 EP disclosed
EP-1730174-B1 PEPTIDE CARRIER FOR DRUG DELIVERY UNIV ILLINOIS (US) 2010-04-21 EP disclosed
WO-2009098475-A1 STRUCTURED SURFACTANT SYSTEMS AND USES THEREOF BIOSUSPENSIONS LIMITED (GB) 2009-08-13 WO disclosed
EP-1042003-A1 DELIVERY OF LONG LASTING THERAPEUTIC AGENTS BY FORMING COVALENT ATTACHMENTS IN VIVO Conjuchem, Inc. (CA) 2000-10-11 EP disclosed
EP-0981328-A1 EMULSION VEHICLE FOR POORLY SOLUBLE DRUGS SONUS PHARMACEUTICALS, INC. (US) 2000-03-01 EP disclosed
WO-1999048536-A2 DELIVERY OF LONG LASTING THERAPEUTIC AGENTS BY FORMING COVALENT ATTACHMENTS IN VIVO CONJUCHEM, INC. (CA) 1999-09-30 WO disclosed
WO-1998030205-A9 EMULSION VEHICLE FOR POORLY SOLUBLE DRUGS 1998-12-30 WO disclosed
WO-1998030205-A1 EMULSION VEHICLE FOR POORLY SOLUBLE DRUGS SONUS PHARMACEUTICALS, INC. (US) 1998-07-16 WO disclosed
US-4816247-A FOR INJECTIONS AMERICAN CYANAMID COMPANY (US) 1989-03-28 US disclosed
US-4784845-A FAT EMULSIONS WITH BENZYL ALCOHOL FOR DRUGS AMERICAN CYANAMID COMPANY (US) 1988-11-15 US disclosed
EP-0214501-A2 Emulsion compositions for administration of sparingly water soluble ionizable basic hydrophobic drugs AMERICAN CYANAMID COMPANY (US) 1987-03-18 EP disclosed
US-4550169-A ANTITUMOR AND ANTICARCINOGENIC AGENTS AMERICAN CYANAMID COMPANY (US) 1985-10-29 US disclosed
EP-0146711-A2 2-hydrazino-1H-imidazoles AMERICAN CYANAMID COMPANY (US) 1985-07-03 EP disclosed