Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SAE1 | Q9UBE0 | 20/20 | 0.47 |
| ▸ | UBA2 | Q9UBT2 | 20/20 | 0.47 |
| ▸ | NAE1 | Q13564 | 14/20 | 0.47 |
| ▸ | UBA3 | Q8TBC4 | 14/20 | 0.47 |
| ▸ | CA1 | P00915 | 2/20 | 0.39 |
| ▸ | CA2 | P00918 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17429042 | 0.86 | SAE1 (0.51) | SAE1UBA2NAE1UBA3CA1 | |
| SCHEMBL17421410 | 0.86 | SAE1 (0.47) | SAE1UBA2NAE1UBA3CA1 | |
| SCHEMBL17429043 | 0.82 | SAE1 (0.51) | SAE1UBA2NAE1UBA3CA1 | |
| SCHEMBL17410378 | 0.80 | SAE1 (0.47) | SAE1UBA2NAE1UBA3 | |
| SCHEMBL23192724 | 0.77 | SAE1 (0.75) | SAE1UBA2NAE1UBA3CA1 | |
| SCHEMBL17398738 | 0.77 | SAE1 (0.75) | SAE1UBA2NAE1UBA3CA1 | |
| SCHEMBL17421685 | 0.77 | SAE1 (0.44) | SAE1UBA2NAE1UBA3CA1 | |
| SCHEMBL17421956 | 0.77 | SAE1 (0.44) | SAE1UBA2NAE1UBA3CA1 | |
| SCHEMBL17429044 | 0.76 | SAE1 (0.47) | SAE1UBA2NAE1UBA3CA1 | |
| SCHEMBL17421306 | 0.76 | SAE1 (0.45) | SAE1UBA2NAE1UBA3CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016004136-A1 | HETEROARYL COMPOUNDS USEFUL AS INHIBITORS OF SUMO ACTIVATING ENZYME | DUFFEY MATTHEW O (US) | 2016-01-07 | — | — | WO | disclosed |