⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5438089 | 0.68 | — | — | |
| SCHEMBL5728116 | 0.68 | — | — | |
| SCHEMBL126 | 0.68 | — | — | |
| SCHEMBL11523834 | 0.68 | — | — | |
| SCHEMBL15033447 | 0.67 | — | — | |
| SCHEMBL8156740 | 0.63 | — | — | |
| Chloromethane SCHEMBL5050446 | 0.63 | — | — | |
| SCHEMBL8462179 | 0.63 | — | — | |
| SCHEMBL22394670 | 0.63 | — | — | |
| SCHEMBL359683 | 0.63 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2389383-A2 | BICYCLIC HETEROCYCLIC SPIRO COMPOUNDS | ISRAEL INSTITUTE FOR BIOLOGICAL RESEARCH (IL) | 2011-11-30 | — | — | EP | disclosed |
| US-8038638-B2 | Plasma detoxification and volume control system and methods of use | HEMOLIFE MEDICAL, INC. (US) | 2011-10-18 | — | — | US | disclosed |
| WO-2010084499-A2 | BICYCLIC HETEROCYCLIC SPIRO COMPOUNDS | ISRAEL INSTITUTE FOR BIOLOGICAL RESEARCH (IL) | 2010-07-29 | — | — | WO | disclosed |