Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | S1PR1 | P21453 | 20/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1739253 | 0.87 | S1PR1 (0.49) | S1PR1 | |
| SCHEMBL1740692 | 0.84 | S1PR1 (0.46) | S1PR1 | |
| SCHEMBL12154388 | 0.83 | S1PR1 (0.46) | S1PR1 | |
| SCHEMBL1739711 | 0.81 | S1PR1 (0.50) | S1PR1 | |
| SCHEMBL1741030 | 0.79 | S1PR1 (0.40) | S1PR1 | |
| SCHEMBL1740965 | 0.78 | S1PR1 (0.45) | S1PR1 | |
| SCHEMBL1741559 | 0.78 | S1PR1 (0.45) | S1PR1 | |
| SCHEMBL1738109 | 0.77 | S1PR1 (0.47) | S1PR1 | |
| SCHEMBL12154476 | 0.75 | S1PR1 (0.41) | S1PR1 | |
| SCHEMBL1741080 | 0.73 | S1PR1 (0.39) | S1PR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2390252-A1 | New pyrazole derivatives | Almirall, S.A. (ES) | 2011-11-30 | — | — | EP | claimed |
| WO-2011144338-A1 | PYRAZOLE DERIVATIVES AS S1P1 AGONISTS | ALMIRALL, S.A. (ES) | 2011-11-24 | — | — | WO | claimed |
| EP-2390252-A1 | New pyrazole derivatives | Almirall, S.A. (ES) | 2011-11-30 | — | — | EP | disclosed |
| EP-2390252-A1 | New pyrazole derivatives | Almirall, S.A. (ES) | 2011-11-30 | — | — | EP | disclosed |
| WO-2011144338-A1 | PYRAZOLE DERIVATIVES AS S1P1 AGONISTS | ALMIRALL, S.A. (ES) | 2011-11-24 | — | — | WO | disclosed |
| WO-2011144338-A1 | PYRAZOLE DERIVATIVES AS S1P1 AGONISTS | ALMIRALL, S.A. (ES) | 2011-11-24 | — | — | WO | disclosed |