⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21939213 | 0.83 | TSHR (0.41) | — | |
| SCHEMBL23945291 | 0.81 | TSHR (0.44) | — | |
| SCHEMBL19850554 | 0.81 | TSHR (0.44) | — | |
| SCHEMBL21938814 | 0.81 | TSHR (0.44) | — | |
| SCHEMBL25658755 | 0.80 | TSHR (0.33) | — | |
| SCHEMBL24503106 | 0.77 | — | — | |
| SCHEMBL4582548 | 0.76 | MEN1 (0.43) | — | |
| SCHEMBL6905450 | 0.76 | — | — | |
| SCHEMBL25458561 | 0.75 | TSHR (0.38) | — | |
| SCHEMBL28546966 | 0.75 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10344281-B2 | Functionally-modified oligonucleotides and subunits thereof | SAREPTA THERAPEUTICS, INC. (US) | 2019-07-09 | — | — | US | disclosed |
| US-20180223278-A1 | Functionally-Modified Oligonucleotides And Subunits Thereof | JPMORGAN CHASE BANK, N.A. AS ADMINISTRATIVE AGENT | 2018-08-09 | — | — | US | disclosed |
| US-9580400-B2 | Cannabinergic nitrate esters and related analogs | NORTHEASTERN UNIVERSITY (US) | 2017-02-28 | — | — | US | disclosed |
| US-20160002195-A1 | CANNABINERGIC NITRATE ESTERS AND RELATED ANALOGS | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2016-01-07 | — | — | US | disclosed |