SCHEMBL17416355

SCHEMBL17416355

CNC(=O)c1ccc(-c2cnc3c(NCCOC)cc(Oc4ccc(OC)c(F)c4)nn23)cc1C

nearest known ligand 0.69

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
TTK P33981 19/20 0.69
FYN P06241 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL458744 0.94 TTK (0.61) TTK
SCHEMBL15556387 0.93 TTK (0.60) TTK
SCHEMBL15556189 0.93 TTK (0.67) TTKFYN
SCHEMBL17590110 0.93 TTK (0.67) TTKFYN
SCHEMBL462607 0.92 TTK (0.70) TTK
SCHEMBL15556862 0.87 TTK (0.60) TTK
SCHEMBL459403 0.87 TTK (0.55) TTK
SCHEMBL17590108 0.87 TTK (0.59) TTKFYN
SCHEMBL462307 0.86 TTK (0.70) TTK
SCHEMBL456224 0.86 TTK (0.78) TTKFYN

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2614063-B1 SUBSTITUTED IMIDAZOPYRIDAZINES BAYER IP GMBH (DE) 2016-01-13 EP disclosed
EP-2614063-B1 SUBSTITUTED IMIDAZOPYRIDAZINES BAYER IP GMBH (DE) 2016-01-13 EP disclosed