Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCB1 | P08183 | 4/20 | 0.53 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | KCNK3 | O14649 | 1/20 | 0.38 |
| ▸ | KCNK9 | Q9NPC2 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7067587 | 0.88 | ABCB1 (0.64) | ABCB1NPC1RAB9AKCNK3KCNK9 | |
| SCHEMBL17416625 | 0.88 | ABCB1 (0.52) | ABCB1NPC1RAB9AKCNK3KCNK9 | |
| SCHEMBL2482845 | 0.87 | ABCB1 (0.51) | ABCB1NPC1RAB9A | |
| SCHEMBL9099071 | 0.86 | ABCB1 (0.53) | ABCB1NPC1RAB9AKCNK3KCNK9 | |
| SCHEMBL17416606 | 0.82 | ABCB1 (0.56) | ABCB1NPC1RAB9AKCNK3KCNK9 | |
| SCHEMBL14688168 | 0.79 | ABCB1 (0.43) | ABCB1NPC1RAB9AKCNK3KCNK9 | |
| SCHEMBL18091864 | 0.79 | ABCB1 (0.69) | ABCB1 | |
| SCHEMBL5057079 | 0.79 | ABCB1 (0.80) | ABCB1 | |
| SCHEMBL9099193 | 0.79 | ABCB1 (0.49) | ABCB1KCNK3KCNK9 | |
| SCHEMBL9232983 | 0.77 | ABCB1 (0.48) | ABCB1NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2460786-B1 | Bioavailable diacylhydrazine ligands for modulating the expression of exogenous genes via an ecdysone receptor complex | INTREXON CORP (US) | 2016-01-13 | — | — | EP | disclosed |