SCHEMBL17416640

SCHEMBL17416640

CCC(N(NC(=O)c1cc(C)cc(C)c1)C(=O)c1cccc(C)c1C)C(C)(C)C

nearest known ligand 0.55

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
ABCB1 P08183 7/20 0.46
CYP3A4 P08684 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL669093 0.91 ABCB1 (0.51) ABCB1CYP3A4
SCHEMBL28253730 0.88 ABCB1 (0.58) ABCB1
SCHEMBL5056927 0.86 ABCB1 (0.42) ABCB1
SCHEMBL27818767 0.83 ABCB1 (0.51) ABCB1CYP3A4
SCHEMBL17604632 0.80 ABCB1 (0.49) ABCB1
SCHEMBL18091873 0.80 NPC1 (0.39) ABCB1CYP3A4
SCHEMBL10721628 0.79 ABCB1 (0.53) ABCB1CYP3A4
SCHEMBL29684613 0.79 ABCB1 (0.66) ABCB1
SCHEMBL668812 0.79 ABCB1 (0.66) ABCB1
SCHEMBL27818769 0.77 ABCB1 (0.40) ABCB1CYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2460786-B1 Bioavailable diacylhydrazine ligands for modulating the expression of exogenous genes via an ecdysone receptor complex INTREXON CORP (US) 2016-01-13 EP disclosed