⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Phosphoric Acid SCHEMBL19100745 | 0.96 | — | — | |
| SCHEMBL18084219 | 0.87 | — | — | |
| SCHEMBL17417626 | 0.87 | — | — | |
| SCHEMBL17417703 | 0.86 | — | — | |
| SCHEMBL17417771 | 0.86 | KCNH2 (0.73) | — | |
| SCHEMBL17417648 | 0.86 | — | — | |
| SCHEMBL17417647 | 0.86 | — | — | |
| Hydrochloric Acid SCHEMBL17417727 | 0.86 | — | — | |
| Hydrochloric Acid SCHEMBL17417783 | 0.85 | — | — | |
| Hydrochloric Acid SCHEMBL17417758 | 0.85 | KCNH2 (0.72) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017120532-A1 | POLYMORPHS OF A PHOSPHATE SALT OF QUINUCLIDIN-4-YLMETHYL 4-METHYL-1H-INDOLE-3-CARBOXYLATE AND USES THEREOF | ALPHARMAGEN, LLC (US) | 2017-07-13 | — | — | WO | disclosed |
| WO-2017120532-A1 | POLYMORPHS OF A PHOSPHATE SALT OF QUINUCLIDIN-4-YLMETHYL 4-METHYL-1H-INDOLE-3-CARBOXYLATE AND USES THEREOF | ALPHARMAGEN, LLC (US) | 2017-07-13 | — | — | WO | disclosed |
| US-20170166561-A1 | QUINUCLIDINE COMPOUNDS FOR MODULATING ALPHA7-NICOTINIC ACETYLCHOLINE RECEPTOR ACTIVITY | ALPHARMAGEN LLC (US) | 2017-06-15 | — | — | US | disclosed |
| US-20170166561-A1 | QUINUCLIDINE COMPOUNDS FOR MODULATING ALPHA7-NICOTINIC ACETYLCHOLINE RECEPTOR ACTIVITY | ALPHARMAGEN LLC (US) | 2017-06-15 | — | — | US | disclosed |
| US-9434724-B2 | Quinuclidines for modulating alpha 7 activity | ALPHARMAGEN, LLC (US) | 2016-09-06 | — | — | US | disclosed |
| US-9434724-B2 | Quinuclidines for modulating alpha 7 activity | ALPHARMAGEN, LLC (US) | 2016-09-06 | — | — | US | disclosed |
| US-20160009706-A1 | QUINUCLIDINES FOR MODULATING ALPHA 7 ACTIVITY | ALPHARMAGEN, LLC | 2016-01-14 | — | — | US | disclosed |
| US-20160009706-A1 | QUINUCLIDINES FOR MODULATING ALPHA 7 ACTIVITY | ALPHARMAGEN, LLC | 2016-01-14 | — | — | US | disclosed |