Known targets — ChEMBL curated mechanism
ACHECHRM1CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNG
The experimentally established mechanism targets of Iodide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10833746 | 0.82 | — | — | |
| SCHEMBL10799533 | 0.82 | — | — | |
| SCHEMBL11337218 | 0.82 | — | — | |
| SCHEMBL11058166 | 0.82 | — | — | |
| SCHEMBL4251926 | 0.82 | — | — | |
| SCHEMBL24477 | 0.82 | — | — | |
| SCHEMBL14910333 | 0.82 | — | — | |
| Iodide SCHEMBL130366 | 0.82 | — | — | |
| SCHEMBL10941307 | 0.82 | — | — | |
| SCHEMBL18575151 | 0.67 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1481264-B1 | X-RAY IMAGING DEVICE | VARIAN MED SYS INC (US) | 2016-03-09 | — | — | EP | disclosed |
| EP-2388622-A2 | X-ray imaging device | Varian Medical Systems Inc. (US) | 2011-11-23 | — | — | EP | disclosed |
| US-20110254960-A1 | IMAGE CONVERTER | ROBERT BOSCH GMBH (DE) | 2011-10-20 | — | — | US | disclosed |
| EP-1481264-A4 | X-RAY IMAGING DEVICE | VARIAN MED SYS TECH INC (US) | 2008-01-02 | — | — | EP | disclosed |
| US-7122804-B2 | X-ray imaging device | VARIAN MEDICAL SYSTEMS TECHNOLOGIES, INC. (US) | 2006-10-17 | — | — | US | disclosed |
| US-20050285044-A1 | X-RAY IMAGING DEVICE | VAREX IMAGING CORPORATION | 2005-12-29 | — | — | US | disclosed |
| EP-1481264-A1 | X-RAY IMAGING DEVICE | Varian Medical Systems Technologies, Inc. (US) | 2004-12-01 | — | — | EP | disclosed |
| WO-2003071307-A1 | X-RAY IMAGING DEVICE | VARIAN MEDICAL SYSTEMS TECHNOLOGIES, INC. (US) | 2003-08-28 | — | — | WO | disclosed |