SCHEMBL1742386

SCHEMBL1742386

CC1(C)CCC(CN2CCN(c3ccc(C(=O)N[S+]([O-])c4cccc(Cl)c4)c(Oc4ccc5[nH]ccc5c4)c3)CC2)=C(c2ccc(Cl)cc2)C1

nearest known ligand 0.73

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
▸ BCL2 P10415 3/20 0.63

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1958650 0.89 BCL2 (0.71) BCL2
SCHEMBL1743338 0.87 BCL2 (0.76) BCL2
SCHEMBL30467934 0.86 BCL2 (0.67) BCL2
SCHEMBL1701562 0.86 BCL2 (0.67) BCL2
SCHEMBL1700059 0.86 BCL2 (0.65) BCL2
SCHEMBL1957047 0.86 BCL2 (0.74) BCL2
SCHEMBL1955777 0.86 BCL2 (0.65) BCL2
SCHEMBL1957655 0.85 BCL2 (0.69) BCL2
SCHEMBL1742374 0.85 BCL2 (0.75) BCL2
SCHEMBL1957240 0.85 BCL2 (0.65) BCL2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2387560-A2 APOPTOSIS-INDUCING AGENTS FOR THE TREATMENT OF CANCER AND IMMUNE AND AUTOIMMUNE DISEASES Abbott Laboratories (US) 2011-11-23 — — EP disclosed
US-8042193-B1 Systems and methods for controlling data access by use of a universal anonymous identifier Albright Associates (US) 2011-10-18 — — US disclosed
WO-2010083441-A2 APOPTOSIS-INDUCING AGENTS FOR THE TREATMENT OF CANCER AND IMMUNE AND AUTOIMMUNE DISEASES ABBOTT LABORATORIES (US) 2010-07-22 — — WO disclosed
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