Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 20/20 | 0.63 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17113789 | 0.91 | MAPK1 (0.64) | MAPK1 | |
| SCHEMBL16964521 | 0.90 | MAPK1 (0.62) | MAPK1 | |
| SCHEMBL16965656 | 0.88 | MAPK1 (0.62) | MAPK1 | |
| SCHEMBL16965598 | 0.88 | MAPK1 (0.62) | MAPK1 | |
| SCHEMBL16965576 | 0.88 | MAPK1 (0.61) | MAPK1 | |
| SCHEMBL16965574 | 0.88 | MAPK1 (0.61) | MAPK1 | |
| SCHEMBL16965030 | 0.88 | MAPK1 (0.61) | MAPK1 | |
| SCHEMBL16965032 | 0.88 | MAPK1 (0.61) | MAPK1 | |
| SCHEMBL16964807 | 0.87 | MAPK1 (0.64) | MAPK1 | |
| SCHEMBL16964804 | 0.87 | MAPK1 (0.64) | MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9233979-B2 | Compounds that are ERK inhibitors | MERCK SHARP & DOHME CORP. (US) | 2016-01-12 | — | — | US | disclosed |