Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | MAOA | P21397 | 1/20 | 0.36 |
| ▸ | MAOB | P27338 | 1/20 | 0.36 |
| ▸ | ITGB3 | P05106 | 5/20 | 0.34 |
| ▸ | ITGA2B | P08514 | 5/20 | 0.34 |
| ▸ | ECE1 | P42892 | 1/20 | 0.34 |
| ▸ | CTSS | P25774 | 2/20 | 0.34 |
| ▸ | CTSK | P43235 | 2/20 | 0.34 |
| ▸ | CA12 | O43570 | 2/20 | 0.34 |
| ▸ | CA1 | P00915 | 2/20 | 0.34 |
| ▸ | CA2 | P00918 | 2/20 | 0.34 |
| ▸ | CA9 | Q16790 | 2/20 | 0.34 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | SIRT5 | Q9NXA8 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15339881 | 0.83 | TDP1 (0.42) | MEN1GAAKMT2ATDP1MAOA | |
| SCHEMBL156911 | 0.82 | GAA (0.58) | MEN1GAAKMT2ATDP1MAOA | |
| Succinic Acid SCHEMBL29429364 | 0.80 | GAA (0.56) | MEN1GAAKMT2ATDP1MAOA | |
| SCHEMBL21834873 | 0.80 | GAA (0.56) | MEN1GAAKMT2ATDP1MAOA | |
| SCHEMBL19487375 | 0.80 | TDP1 (0.60) | MEN1GAAKMT2ATDP1MAOA | |
| SCHEMBL19487376 | 0.79 | TDP1 (0.39) | MEN1GAAKMT2ATDP1MAOA | |
| SCHEMBL18233922 | 0.78 | KMT2A (0.48) | MEN1GAAKMT2ATDP1MAOA | |
| SCHEMBL12155265 | 0.78 | TDP1 (0.50) | MEN1GAAKMT2ATDP1MAOA | |
| SCHEMBL4854621 | 0.78 | TDP1 (0.39) | MEN1GAAKMT2ATDP1CA12 | |
| SCHEMBL17234179 | 0.76 | MEN1 (0.39) | MEN1GAAKMT2ATDP1MAOA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9234007-B2 | RGD mimetic γ-AApeptides and methods of use | UNIVERSITY OF SOUTH FLORIDA (US) | 2016-01-12 | — | — | US | disclosed |