Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GLP1R | P43220 | 8/20 | 0.53 |
| ▸ | SELP | P16109 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | MMP2 | P08253 | 5/20 | 0.35 |
| ▸ | MMP9 | P14780 | 5/20 | 0.35 |
| ▸ | MMP8 | P22894 | 4/20 | 0.35 |
| ▸ | MMP12 | P39900 | 4/20 | 0.35 |
| ▸ | MMP14 | P50281 | 4/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | PCNA | P12004 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16062708 | 0.95 | GLP1R (0.47) | GLP1RSELPSMN1; SMN2MMP2MMP9 | |
| SCHEMBL16772149 | 0.91 | GLP1R (0.52) | GLP1RMMP2MMP9MMP8MMP12 | |
| SCHEMBL25454221 | 0.91 | GLP1R (0.51) | GLP1RMMP2MMP9MMP8MMP12 | |
| SCHEMBL14240744 | 0.90 | GLP1R (0.50) | GLP1RMMP2MMP9MMP8MMP12 | |
| SCHEMBL27120318 | 0.90 | GLP1R (0.50) | GLP1RMMP2MMP9MMP8MMP12 | |
| SCHEMBL27120257 | 0.90 | GLP1R (0.50) | GLP1RSMN1; SMN2MEN1KMT2AALDH1A1 | |
| SCHEMBL71086 | 0.90 | GLP1R (0.50) | GLP1RMMP2MMP9MMP8MMP12 | |
| SCHEMBL27119968 | 0.90 | GLP1R (0.50) | GLP1RSMN1; SMN2MEN1KMT2AALDH1A1 | |
| SCHEMBL21440827 | 0.90 | GLP1R (0.50) | GLP1RMMP2MMP9MMP8MMP12 | |
| SCHEMBL21096839 | 0.89 | GLP1R (0.52) | GLP1RMMP2MMP9MMP8MMP12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9234192-B2 | Conjugated proteins | NOVO NORDISK A/S (DK) | 2016-01-12 | — | — | US | disclosed |