SCHEMBL17427593

SCHEMBL17427593

c1ccc(-c2nc(-c3ccccc3)nc(-c3ccc4c(c3)c3c5ccccc5c5c6ccccc6sc5c3n4-c3nc(-c4ccccc4)nc(-c4ccccc4)n3)n2)cc1

nearest known ligand 0.34

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
LIMK1 P53667 1/20 0.32
TNKS O95271 2/20 0.31
TNKS2 Q9H2K2 2/20 0.31
MEN1 O00255 2/20 0.31
MAPT P10636 2/20 0.31
KMT2A Q03164 2/20 0.31
ALDH1A1 P00352 1/20 0.31
HPGD P15428 1/20 0.31
ATM Q13315 2/20 0.30
L3MBTL1 Q9Y468 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17427590 0.93 KDM4E (0.33) LIMK1MEN1KMT2AALDH1A1
SCHEMBL15138910 0.92 LIMK1 (0.38) LIMK1MEN1MAPTKMT2AALDH1A1
SCHEMBL16206306 0.92 ATM (0.31) LIMK1TNKSTNKS2MEN1MAPT
SCHEMBL17427597 0.91 LIMK1 (0.33) LIMK1TNKSTNKS2
SCHEMBL18086397 0.91 TNKS (0.32) LIMK1TNKSTNKS2MEN1KMT2A
SCHEMBL21707294 0.91 TNKS (0.32) LIMK1TNKSTNKS2MEN1KMT2A
SCHEMBL16206308 0.91 TNKS (0.33) TNKSTNKS2MEN1MAPTKMT2A
SCHEMBL18086402 0.91 LIMK1 (0.33) LIMK1TNKSTNKS2MAPTATM
SCHEMBL22199909 0.90 LIMK1 (0.32) LIMK1
SCHEMBL18086404 0.90 KDM4E (0.35) ATML3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9401484-B2 Organic light-emitting device having increased electron transport ability of an electron transport region SAMSUNG DISPLAY CO., LTD. (KR) 2016-07-26 US disclosed
US-9401484-B2 Organic light-emitting device having increased electron transport ability of an electron transport region SAMSUNG DISPLAY CO., LTD. (KR) 2016-07-26 US disclosed
US-9246111-B1 Organic light-emitting device SAMSUNG DISPLAY CO., LTD. (KR) 2016-01-26 US disclosed
US-9246111-B1 Organic light-emitting device SAMSUNG DISPLAY CO., LTD. (KR) 2016-01-26 US disclosed
US-20160020412-A1 ORGANIC LIGHT-EMITTING DEVICE SAMSUNG DISPLAY CO., LTD. (KR) 2016-01-21 US disclosed
US-20160020412-A1 ORGANIC LIGHT-EMITTING DEVICE SAMSUNG DISPLAY CO., LTD. (KR) 2016-01-21 US disclosed
US-20160013430-A1 ORGANIC LIGHT-EMITTING DEVICE SAMSUNG DISPLAY CO., LTD. (KR) 2016-01-14 US disclosed
US-20160013430-A1 ORGANIC LIGHT-EMITTING DEVICE SAMSUNG DISPLAY CO., LTD. (KR) 2016-01-14 US disclosed