SCHEMBL17427622

SCHEMBL17427622

c1ccc(-c2nc(-c3ccccc3)nc(-c3ccc(-n4c5ccccc5c5ccc6c(ccc7c8ccccc8oc76)c54)cc3)n2)cc1

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 10/20 0.39
TSHR P16473 5/20 0.39
KDM4E B2RXH2 4/20 0.37
ATM Q13315 1/20 0.37
L3MBTL1 Q9Y468 1/20 0.37
ALDH1A1 P00352 8/20 0.37
POLB P06746 3/20 0.37
HPGD P15428 2/20 0.37
LMNA P02545 5/20 0.36
HSD17B10 Q99714 3/20 0.36
MAPK1 P28482 2/20 0.36
NPSR1 Q6W5P4 3/20 0.36
KMT2A Q03164 6/20 0.36
MEN1 O00255 5/20 0.36
USP2 O75604 1/20 0.35
HTT P42858 1/20 0.35
CYP1A2 P05177 1/20 0.34
CYP3A4 P08684 1/20 0.34
CYP2C9 P11712 1/20 0.34
CYP2C19 P33261 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16521286 0.95 MAPT (0.39) MAPTTSHRKDM4EATML3MBTL1
SCHEMBL16521284 0.94 MAPT (0.38) MAPTTSHRKDM4EATML3MBTL1
SCHEMBL23595276 0.94 MAPT (0.38) MAPTTSHRKDM4EATML3MBTL1
SCHEMBL16521285 0.94 MAPT (0.38) MAPTTSHRKDM4EATML3MBTL1
SCHEMBL18564550 0.93 KDM4E (0.36) MAPTTSHRKDM4EATML3MBTL1
SCHEMBL17809134 0.92 MAPT (0.37) MAPTTSHRKDM4EATML3MBTL1
SCHEMBL22192548 0.92 KDM4E (0.38) MAPTTSHRKDM4EATML3MBTL1
SCHEMBL22192327 0.92 KDM4E (0.38) MAPTTSHRKDM4EATML3MBTL1
SCHEMBL17427620 0.91 KDM4E (0.42) MAPTTSHRKDM4EATML3MBTL1
SCHEMBL24217097 0.91 MAPT (0.36) MAPTTSHRKDM4EATML3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9401484-B2 Organic light-emitting device having increased electron transport ability of an electron transport region SAMSUNG DISPLAY CO., LTD. (KR) 2016-07-26 US disclosed
US-9401484-B2 Organic light-emitting device having increased electron transport ability of an electron transport region SAMSUNG DISPLAY CO., LTD. (KR) 2016-07-26 US disclosed
US-9246111-B1 Organic light-emitting device SAMSUNG DISPLAY CO., LTD. (KR) 2016-01-26 US disclosed
US-9246111-B1 Organic light-emitting device SAMSUNG DISPLAY CO., LTD. (KR) 2016-01-26 US disclosed
US-20160020412-A1 ORGANIC LIGHT-EMITTING DEVICE SAMSUNG DISPLAY CO., LTD. (KR) 2016-01-21 US disclosed
US-20160020412-A1 ORGANIC LIGHT-EMITTING DEVICE SAMSUNG DISPLAY CO., LTD. (KR) 2016-01-21 US disclosed
US-20160013430-A1 ORGANIC LIGHT-EMITTING DEVICE SAMSUNG DISPLAY CO., LTD. (KR) 2016-01-14 US disclosed
US-20160013430-A1 ORGANIC LIGHT-EMITTING DEVICE SAMSUNG DISPLAY CO., LTD. (KR) 2016-01-14 US disclosed