SCHEMBL17427640

SCHEMBL17427640

c1ccc(-c2ccc(-n3c4ccc(N(c5ccccc5)c5ccccc5)cc4c4ccc5c(ccc6c7ccccc7sc65)c43)cc2)cc1

nearest known ligand 0.32

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
TNKS O95271 1/20 0.32
TNKS2 Q9H2K2 1/20 0.32
ALOX5 P09917 1/20 0.32
HSD17B10 Q99714 1/20 0.32
APP P05067 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17427642 0.93
SCHEMBL18645829 0.92 HSD17B10 (0.35) TNKSTNKS2ALOX5HSD17B10APP
SCHEMBL17299604 0.89 HSD17B10 (0.31) HSD17B10
SCHEMBL18647167 0.89 HSD17B10 (0.37) HSD17B10
SCHEMBL18646981 0.88 KDM4E (0.35) ALOX5HSD17B10
SCHEMBL18647166 0.88 HSD17B10 (0.35) TNKSTNKS2ALOX5HSD17B10APP
SCHEMBL18647169 0.88 HSD17B10 (0.35) TNKSTNKS2ALOX5HSD17B10APP
SCHEMBL31657 0.88 HSD17B10 (0.36) TNKSTNKS2ALOX5HSD17B10APP
SCHEMBL18647185 0.88 HSD17B10 (0.32) ALOX5HSD17B10
SCHEMBL17427704 0.87 PMM2 (0.34)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9401484-B2 Organic light-emitting device having increased electron transport ability of an electron transport region SAMSUNG DISPLAY CO., LTD. (KR) 2016-07-26 US disclosed
US-9401484-B2 Organic light-emitting device having increased electron transport ability of an electron transport region SAMSUNG DISPLAY CO., LTD. (KR) 2016-07-26 US disclosed
US-9246111-B1 Organic light-emitting device SAMSUNG DISPLAY CO., LTD. (KR) 2016-01-26 US disclosed
US-9246111-B1 Organic light-emitting device SAMSUNG DISPLAY CO., LTD. (KR) 2016-01-26 US disclosed
US-20160020412-A1 ORGANIC LIGHT-EMITTING DEVICE SAMSUNG DISPLAY CO., LTD. (KR) 2016-01-21 US disclosed
US-20160020412-A1 ORGANIC LIGHT-EMITTING DEVICE SAMSUNG DISPLAY CO., LTD. (KR) 2016-01-21 US disclosed
US-20160013430-A1 ORGANIC LIGHT-EMITTING DEVICE SAMSUNG DISPLAY CO., LTD. (KR) 2016-01-14 US disclosed
US-20160013430-A1 ORGANIC LIGHT-EMITTING DEVICE SAMSUNG DISPLAY CO., LTD. (KR) 2016-01-14 US disclosed